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DOI: 10.1055/s-2008-1081461
© Georg Thieme Verlag KG Stuttgart · New York
Systems Biology and Psychiatry – Modeling Molecular and Cellular Networks of Mental Disorders
Publication History
Publication Date:
28 August 2008 (online)
![](https://www.thieme-connect.de/media/pharmaco/2008S01/lookinside/thumbnails/10.1055-s-2008-1081461-1.jpg)
Abstract
Biological psychiatry has more and more directed it's focus on the involvement of genes and molecules in mental health and disease. On these levels, new approaches in other medical fields are noticed that are collectively dubbed “Systems Biology”. Conceptually, this new paradigm tries to view molecular interactions in cellular networks as dynamic, self-organizing events that eventually result in an ordered maintenance of the whole system. A great deal of applied mathematics is required in systems biology to set up and carry out computer modeling and simulation. In terms of psychiatric research, developing “systems biology of the neuron” could become a pivotal achievement for a better understanding of mental illness on the molecular level. A brief outline of imminent tasks and links between systems biology and biological psychiatry is presented.
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Correspondence
Dr. F. Tretter
Department of Addictions Isar Amper Clincis
Clinic Munich East
85529 Haar/Munich
Germany
Phone: +49/89/4562 37 08
Fax: +49/89/4562 37 08
Email: Felix.Tretter@IAK-KMO.de