Ultrasound thrombolysis

Stefan Pfaffenberger; Branka Devcic-Kuhar; Stefan P. Kastl; Kurt Huber; Gerald Maurer; Johann Wojta; Michael Gottsauner-Wolf

doi:10.1160/TH04-12-0818

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 2005; 94(01): 26-36
DOI: 10.1160/TH04-12-0818

Review Article

Schattauer GmbH

Ultrasound thrombolysis

Stefan Pfaffenberger

¹Department of Internal Medicine II, University of Vienna, Austria

,

Branka Devcic-Kuhar

²Institute of General Physics, Vienna University of Technology, Austria

,

Stefan P. Kastl

¹Department of Internal Medicine II, University of Vienna, Austria

,

Kurt Huber

³3^rd Department of Medicine (Cardiology and Emergency Medicine), Wilhelminenspital, Vienna, Austria

,

Gerald Maurer

¹Department of Internal Medicine II, University of Vienna, Austria

,

Johann Wojta

¹Department of Internal Medicine II, University of Vienna, Austria

,

Michael Gottsauner-Wolf

¹Department of Internal Medicine II, University of Vienna, Austria

› Author Affiliations

Abstract

Summary

Cardiovascular diseases are a major cause of mortality in the developed world. Efficacy of thrombolysis plays an important role in the management of acute myocardial infarction and cerebral insult both in the acute event and in the long-term outcome of these patients. New adjunctive strategies have been tested, therefore, to make thrombolytic therapies more effective and safer. Ultrasound Thrombolysis is a technique which showed promising results under in vitro conditions and in animal studies. Now clinical trials have to prove if it is also feasible for clinical application. This report gives an overview on different technical approaches and their current performances in the clinical setting. All original articles are chronologically ordered in tables providing detailed information on each study concerning experimental design, acoustical parameters and thrombolysis outcome.

Keywords

Ultrasound - thrombolysis - adjunctive therapy - myocardial infarction - stroke - sonothrombolysis

Full Text

References

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