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Thromb Haemost 2005; 94(03): 690-691
DOI: 10.1160/TH05-03-0690
DOI: 10.1160/TH05-03-0690
Letters to the Editor
Vitamin K epoxide reductase (VKORC1) genetic polymorphism is associated to oral anticoagulant overdose
Further Information
Publication History
Received: 17 May 2005
Accepted after major revision: 01 July 2005
Publication Date:
07 December 2017 (online)
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References
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- 4 Rost S, Fregin A, Ivaskevicius V. et. Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2.. Nature 2004; 427: 537-41.
- 5 Sadler JE. Medicine: K is for koagulation.. Nature 2004; 427: 493-4.
- 6 Li T, Chang CY, Jin DY. et al. Identification of the gene for vitamin K epoxide reductase.. Nature 2004; 427: 541-4.
- 7 Bodin L, Verstuyft C, Tregouet DA. et al. Cytochrome P450 2C9 (CYP2C9) and vitamin K epoxide reductase (VKORC1) genotypes as determinants of acenocoumarol sensitivity.. Blood 2005; 106: 135-40.
- 8 D’Andrea G, D’Ambrosio RL, Di Perna P. et al. A polymorphism in the VKORC1 gene is associated with an interindividual variability in the dose-anticoagulant effect of warfarin.. Blood 2005; 105: 645-9.
- 9 Yuan HY, Chen JJ, Lee MT. et al. A novel functional VKORC1 promoter polymorphism is associated with inter-individual and inter-ethnic differences in warfarin sensitivity.. Hum Mol Genet 2005; 14: 1745-51.
- 10 Rieder MJ, Reiner AP, Gage BF. et al. Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose.. N Engl J Med 2005; 352: 2285-93.