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Thromb Haemost 2006; 95(03): 524-534
DOI: 10.1160/TH05-06-0457
Cellular Proteolysis and Oncology
Schattauer GmbH

Direct interaction of the kringle domain of urokinase-type plasminogen activator (uPA) and integrin αvβ3 induces signal transduction and enhances plasminogen activation

Takehiko Tarui
2   Department of Cell Biology, The Scripps Research Institute, La Jolla, California
,
Nobuaki Akakura
1   Department of Dermatology, University of California Davis Medical Center, Sacramento, California
,
Mousumi Majumdar
2   Department of Cell Biology, The Scripps Research Institute, La Jolla, California
,
Nicholas Andronicos
2   Department of Cell Biology, The Scripps Research Institute, La Jolla, California
,
Junichi Takagi
3   Center for Blood Research and Department of Pathology, Harvard Medical School, Boston, Massachussetts
,
Andrew P. Mazar
4   Attenuon, LLC, San Diego, California
,
Khalil Bdeir
5   Departments of Pathology and Laboratory Medicine, University of Pennsylvania, Pennsylvania, USA
,
Alice Kuo
5   Departments of Pathology and Laboratory Medicine, University of Pennsylvania, Pennsylvania, USA
,
Serge V. Yarovoi
5   Departments of Pathology and Laboratory Medicine, University of Pennsylvania, Pennsylvania, USA
,
Douglas B. Cines
5   Departments of Pathology and Laboratory Medicine, University of Pennsylvania, Pennsylvania, USA
,
Yoshikazu Takada
1   Department of Dermatology, University of California Davis Medical Center, Sacramento, California
› Author Affiliations