Plasma peptidome: A new approach for assessing thrombotic risk?

• References

• 1 Svensson AM, Whitely GR, Callas PW. et al. SELDI-TOF plasma profiles distinguish individuals in a protein C-deficient family with thrombotic episodes occuring before age 40. Thromb Haemost 2006; 96: 725-30.
• 2 Petricoin EF, Ardekani AM, Hitt BA. et al. Use of proteomic patterns in serum to identify ovarian cancer. Lancet 2002; 359: 572-7.
• 3 Nelsestuen GL, Zhang Y, Martinez MB. et al. Plasma protein profiling: unique and stable features of individuals. Proteomics 2005; 05: 4012-24.
• 4 Villanueva J, Shaffer DR, Philip J. et al. Differential exoprotease activities confer tumor-specific serum peptidome patterns. J Clin Invest 2006; 116: 271-84.
• 5 Hortin GL. The MALDI-TOF mass spectrometric view of the plasma proteome and peptidome. Clin Chem 2006; 52: 1223-37.
• 6 Rossi L, Martin BM, Horti GL. et al. Inflammatory protein profile during systemic high dose interleukin-2 administration. Proteomics 2006; 06: 709-20.
• 7 Richter R, Schulz-Knappe P, Schrader M. et al. Composition of the peptide fraction in human blood plasma: database of circulating human peptides. J ChromatogrB Biomed Sci Appl 1999; 726: 25-35.