Thrombosis and Haemostasis, Table of Contents Thromb Haemost 2007; 97(03): 329-330DOI: 10.1160/TH07-02-0104 Editorial Focus Schattauer GmbH The clinical significance of circulating tissue factor in prostate cancer Jorge Nieva 1 Scripps Research Institute, La Jolla, California, USA › Author Affiliations Recommend Article Abstract Buy Article Full Text References References 1 Langer F, Chun FKH, Amirkhosravi A. et al. Plasma tissue factor antigen in localized prostate cancer: Distribution, clinical significance and correlation with haemostatic activation markers. Thromb Haemost 2007; 97: 464-470. 2 Falanga A, Gordon SG. Isolation and characterization of cancer procoagulant: a cysteine proteinase from malignant tissue. Biochemistry 1985; 24: 5558-5567. 3 Biro E, Sturk-Maquelin KN, Vogel GM. et al. Human cell-derived microparticles promote thrombus formation in vivo in a tissue factor-dependent manner. J Thromb Haemost 2003; 1: 2561-2568. 4 Broze Jr GJ, Leykam JE, Schwartz BD. et al. Purification of human brain tissue factor. J Biol Chem 1985; 260: 10917-10920. 5 Morrissey JJH, Fakhrai HH, Edgington TTS. Molecular cloning of the cDNA for tissue factor, the cellular receptor for the initiation of the coagulation protease cascade. Cell 1987; 50: 129-135. 6 Harlos KK, Martin DDM, O'Brien DDP. et al. Crystal structure of the extracellular region of human tissue factor. Nature 1994; 370: 662-666. 7 Ruf W, Mueller BM. Thrombin generation and the pathogenesis of cancer. Semin Thromb Hemost 2006; 32 (Suppl. 01) 61-68. 8 Ngo CV, Picha K, McCabe F. et al. CNTO 859, a humanized anti-tissue factor monoclonal antibody, is a potent inhibitor of breast cancer metastasis and tumor growth in xenograft models. Int J Cancer 2007; 120: 1261-1267. 9 Altomare DDF, Rotelli MMT, Pentimone AA. et al. Tissue factor and vascular endothelial growth factor expression in colorectal cancer: relation with cancer recurrence. Colorectal Dis 2007; 9: 133-138. 10 Uno KK, Homma SS, Satoh TT. et al. Tissue factor expression as a possible determinant of thromboembolism in ovarian cancer. Br J Cancer 2007; 96: 290-295. 11 Butenas S, Bouchard BA, Brummel-Ziedins KE. et al. Tissue factor activity in whole blood. Blood 2005; 105: 2764-2770. 12 Han LY, Landen Jr CN, Kamat AA. et al. Preoperative serum tissue factor levels are an independent prognostic factor in patients with ovarian carcinoma. J Clin Oncol 2006; 24: 755-761.