Acute aldosterone infusion enhances thrombosis development in normotensive rats

• References

• 1 Charloux A, Gronfier C, Lonsdorfer-Wolf E. et al. Aldosterone release during the sleep-wake cycle in humans. Am J Physiol 1999; 276: 43-49.
• 2 Farquharson CA, Struthers AD. Aldosterone induces acute andothelial dysfunction in vivo in humans: evidence for an aldosterone-induced vasculopathy. Clin Sci 2002; 103: 425-431.
• 3 Mogielnicki A, Chabielska E, Pawlak R. et al. Angiotensin II enhances thrombosis development in renovascular hypertensive rats. Thromb Haemost 2005; 93: 1069-1076.
• 4 Giles AR. Guidelines for the use of animals in biomedical research. Thromb Haemost 1987; 58: 1078-1084.
• 5 Wickman A, Andersson IJ, Jia J. et al. Endothelial nitric oxide synthase protein is reduced in the renal medulla of two-kidney, one-clip hypertensive rats. J Hypertens 2001; 19: 1665-1673.
• 6 Thohan V, Torre-Amione G, Koerner MM. Aldosterone antagonism and congestive heart failure: a new look at an old therapy. Curr Opin Cardiol 2004; 19: 301-308.
• 7 Jessup M. Aldosterone blockade and heart failure. N Engl J Med 2003; 348: 1380-1382.
• 8 Brown NJ, Nakamura S, Ma L. et al. Aldosterone modulates plasminogen activator inhibitor-1 and glomerulosclerosis in vivo. Kidney Int 2000; 58: 1219-1227.
• 9 Kaminska M, Mogielnicki A, Stankiewicz A. et al. Angiotensin II via AT1 receptor accelerates arterial thrombosis in renovascular hypertensive rats. J Physiol Pharmacol 2005; 56: 571-585.