Thromb Haemost 2007; 98(01): 129-130
DOI: 10.1160/TH07-04-0227
Anniversary Issue Contribution
Schattauer GmbH

Early studies on the coagulogen (clottable protein) of Limulus polyphemus (horseshoe crab)

Nils Olav Solum
1   Research Institute forInternal Medicine (previously calledInstitute forThrombosisResearch), University of Oslo, Norway
,
Erik Mürer
2   Department of Medicine,Temple University,Philadelphia, Pennsylvania, USA
› Author Affiliations
Further Information

Publication History

Received 27 March 2007

Accepted 26 April 2007

Publication Date:
29 November 2017 (online)

 

 
  • References

  • 1 Solum NO. Some characteristics of the clottable protein of Limulus polyphemus blood cells. Thromb Diath Haemorrh 1970; 23: 170-181.
  • 2 Levin J, Bang F. B. Clottable protein in Limulus: Its localization and kinetics of its coagulation by endotoxin. Thromb Diath Haemorrh 1968; 19: 186-97.
  • 3 Solum NO. The coagulogen of Limulus polyphemus hemocytes. A comparison of the clotted and non-clotted forms of themolecule. Thromb Res 1973; 2: 55-69.
  • 4 Miyata T, Hiranaga M, Umezu M. et al. Amino acid sequence of the coagulogen from Limulus polyphemus hemocytes. J Biol Chem 1984; 259: 8924-8933.
  • 5 Mürer E, Levin J, Holme R. Isolation and studies of the granules of the amoebocytes of Limulus polyphemus, the horseshoe crab. J Cell Physiol 1975; 86: 533-542.
  • 6 Iwanaga S. The molecular basis of of innate immunity in the horseshoe crab. Current Opinionin Immunology 2002; 14: 87-95.