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Thromb Haemost 2007; 98(04): 906-907
DOI: 10.1160/TH07-04-0243
Case Report
Schattauer GmbH

Thrombophilia in young patients with cryptogenic stroke and patent foramen ovale (PFO)

Pietro Offelli
1   Clinical Cardiology, Thrombosis Centre, University Hospital, Padova, Italy
,
Mario Zanchetta
2   Division of Cardiology, District Hospital, Cittadella, Italy
,
Luigi Pedon
2   Division of Cardiology, District Hospital, Cittadella, Italy
,
Filippo Marzot
1   Clinical Cardiology, Thrombosis Centre, University Hospital, Padova, Italy
,
Umberto Cucchini
1   Clinical Cardiology, Thrombosis Centre, University Hospital, Padova, Italy
,
Cinzia Pegoraro
1   Clinical Cardiology, Thrombosis Centre, University Hospital, Padova, Italy
,
Sabino Iliceto
1   Clinical Cardiology, Thrombosis Centre, University Hospital, Padova, Italy
,
Vittorio Pengo
1   Clinical Cardiology, Thrombosis Centre, University Hospital, Padova, Italy
› Institutsangaben
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Publikationsverlauf

Received 03. April 2007

Accepted after resubmission 18. Juni 2007

Publikationsdatum:
01. Dezember 2017 (online)

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  • References

  • 1 Leys D, Bandu L, Henon H. et al. Clinical outcome in 287 consecutive young adults (15 to 45 years) with ischemic stroke.. Neurology 2002; 59: 26-33.
    CrossrefPubMedSuche in Google Scholar
  • 2 Overell JR, Bone I, Less KR. Interatrial septal abnormalities and stroke: a meta-analysis of case-control studies.. Neurology 2000; 55: 1172-1179.
    CrossrefPubMedSuche in Google Scholar
  • 3 Kizer JR, Devereux RB. Patent Foramen Ovale in Young Adults with Unexplained Stroke. N Engl J Med 2005; 353: 2361-2372.
    CrossrefPubMedSuche in Google Scholar
  • 4 Stollberger C, Slany J, Schuster I. et al. The prevalence of deep venous thrombosis in patients with suspected paradoxical embolism.. Ann Intern Med 1994; 120: 347-351.
    PubMedSuche in Google Scholar
  • 5 Falk RH. PFO or UFO? The role of a patent foramen ovale in cryptogenic stroke.. Am Heart J 1991; 121: 1264-1266.
    CrossrefPubMedSuche in Google Scholar
  • 6 Lethen H, Flachskampf F, Schneider R. et al. Frequency of deep vein thrombosis in patients with patent foramen ovale and ischemic stroke or transient ischemic attack.. Am J Cardiol 1997; 80: 1066-1069.
    CrossrefPubMedSuche in Google Scholar
  • 7 Cramer S, Rordorf G, Maki J. et al. Increased pelvic vein thrombi in cryptogenic stroke: Results of the paradoxical emboli from large veins in ischemic stroke (PELVIS) study.. Stroke 2004; 35: 46-50.
    PubMedSuche in Google Scholar
  • 8 Adams Jr HP, Bendixen BH, Kappelle LJ. et al. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment.. Stroke 1993; 24: 35-41.
    CrossrefPubMedSuche in Google Scholar
  • 9 Bertina RM, Koeleman BP, Koster T. et al. Mutation in blood coagulation factor V associated with resistance to activated protein C.. Nature 1994; 369: 64-67.
    CrossrefPubMedSuche in Google Scholar
  • 10 Poort SR, Rosendaal FR, Reitsma PH. et al. A common genetic variation in the 3’-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis.. Blood 1996; 88: 3698-3703.
    PubMedSuche in Google Scholar
  • 11 Pengo V, Biasiolo A, Gresele P. et al. on behalf of Participating Centres of Italian Federation of Thrombosis Centres (FCSA). Survey of lupus anticoagulant diagnosis by central evaluation of positive plasma samples.. J Thromb Haemost 2007; 5: 925-930.
    CrossrefPubMedSuche in Google Scholar
  • 12 Pengo V, Biasiolo A, Fior MG. Autoimmune antiphospholipid antibodies are directed against a cryptic epitope expressed when b2-glycoprotein-I is bound to a suitable surface.. Thromb Haemost 1995; 73: 29-34.
    Thieme ConnectPubMedSuche in Google Scholar
  • 13 Miyakis S, Lockshin MD, Atsumi T. et al. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS).. J Thromb Haemost 2006; 4: 295-306.
    CrossrefPubMedSuche in Google Scholar
  • 14 Hankey G, Eikelboom J, van Bockxmeer F. et al. Inherited thrombophilia in ischemic stroke and its pathogenic subtypes.. Stroke 2001; 32: 1793-1799.
    CrossrefPubMedSuche in Google Scholar
  • 15 Carod-Artal FJ, Vilela Nunes S, Portugal D. Thrombophilia and patent foramen ovale in young stroke patients.. Neurologia 2006; 21: 710-716.
    PubMedSuche in Google Scholar
  • 16 Sastry S, Riding G, Morris J. et al. Young Adult Myocardial Infarction and Ischemic Stroke: the role of paradoxical embolism and thrombophilia (The YAMIS Study).. J Am Coll Cardiol 2006; 48: 686-691.
    CrossrefPubMedSuche in Google Scholar
  • 17 Pezzini A, Del Zotto E, Magoni M. et al. Inherited thrombophilic disorders in young adults with ischemic stroke and patent foramen ovale.. Stroke 2003; 34: 28-33.
    CrossrefPubMedSuche in Google Scholar
  • 18 Karttunen V, Hiltunen L, Rasi V. et al. Factor V Leiden and prothrombin gene mutation may predispose to paradoxical embolism in subjects with patent foramen ovale.. Blood Coagul Fibrinolysis 2003; 14: 261-268.
    PubMedSuche in Google Scholar
  • 19 Dodge SM, Hassell K, Anderson CA. et al. Antiphospholipid antibodies are common in patients referred for percutaneous patent foramen ovale closure.. Catheter Cardiovasc Interv 2004; 61: 123-127.
    CrossrefPubMedSuche in Google Scholar
  • 20 Belvis R, Santamaria A, Marti-Fabregas J. et al. Diagnostic yield of prothrombotic state studies in cryptogenic stroke.. Acta Neurol Scand 2006; 114: 250-253.
    CrossrefPubMedSuche in Google Scholar
  • 21 Cramer S. Patent foramen ovale and stroke: prognosis and treatment in young adults.. J Thromb Thrombolysis 2005; 20: 85-91.
    CrossrefPubMedSuche in Google Scholar