Burn injuries – is antithrombin back on stage in critical care?

References
1 Lavrentieva A, Kontakiotis T, Bitzani M. et al. The efficacy of antithrombin administration in the acute phase of burn injury. Thromb Haemost 2008; 286-290.
2 Alkjaersig N, Fletcher AP, Peden JC. et al. Fibrinogen catabolism in burned patients. Trauma 1980; 20: 154-159.
3 Kowal-Vern A, Gamelli RL, Walenga JM. et al. The effect of burn wound size on hemostasis: a correlation of the hemostatic changes to the clinical state. Trauma 1992; 33: 50-57.
4 Ueyama M, Yamamoto I, Sawada Y. Disseminated intravascular coagulation in the early stage after severe burn: the role of excessive thrombin generation. Nippon Geka Gakkai zasshi 1991; 92: 907-912.
5 Neely AN, Warden GD, Rieman M. et al. Components of the increased circulating proteolytic activity in pediatric burn patients. Trauma 1992; 33: 807-812.
6 Prager MD, Baxter CR, Hartline B. Proteolytic activity in burn wound exudates and comparison of fibrin degradation products and protease inhibitors in exudates and sera. J Burn Care Rehabil 1994; 15: 130-136.
7 Neely AN, Miller RG, Holder IA. Proteolytic activity and fatal gram-negative sepsis in burned mice: effect of exogenous proteinase inhibition. Inf Immun 1994; 62: 2158-2164.
8 Okada Y, Zuo XJ, Marchevsky AM. et al. Anti-thrombin III treatment improves parameters of acute inflammation in a highly histoincompatible model of rat lung allograft rejection. Transplantation 1999; 67: 526-528.
9 Danielsson P, Nilsson L, Nettelblad H. et al. Is there a need for antithrombin III substitution early after burn injury?. Burns 1997; 23: 300-305.
10 Kowal-Vern A, McGill V, Walenga JM. et al. Antithrombin(H) concentrate infusions are safe and effective in patients with thermal injuries. J Burn Care Reha-bil 2000; 21: 115-127.
11 Kowal-Vern A, Walenga JM, McGill V. et al. The impact of antithrombin (H) concentrate infusions on pulmonary function in the acute phase of thermal injury. Burns 2001; 27: 52-60.
12 Murakami K, McGuire R, Cox RA. et al. Recombinant antithrombin attenuates pulmonary inflamemation following smoke inhalation and pneumonia in sheep. Crit Care Med 2003; 31: 577-583.
13 Murakami K, Enkhbaatar P, Shimoda K. et al. High-dose heparin fails to improve acute lung injury following smoke inhalation in sheep. Clin Sci (Lond) 2003; 104: 349-356.
14 Del Principe D. Antithrombin III in burned children. Minerva Anestesiologica 2003; 69: 376-380.
15 Niedermayr M, Schramm W, Kamolz L. et al. Antithrombin deficiency and its relationship to severe burns. Burns 2007; 33: 173-178.
16 Lavrentieva A, Kontakiotis T, Bitzani M. et al. Early coagulation disorders after severe burn injury: impact on mortality. Int Care Med 2008; 34: 700-706.
17 Warren BL, Eid A, Singer P. et al. Caring for the critically ill patient. High-dose antithrombin III in severe sepsis: a randomized controlled trial. J Am Med Assoc 2001; 286: 1869-1878.
18 Kienast J, Juers M, Wiedermann CJ. et al. Treatment effects of high-dose antithrombin without concomitant heparin in patients with severe sepsis with or without disseminated intravascular coagulation. J Thromb Haemost 2006; 04: 90-97.