Thrombotic complications in thalassemic patients: Contribution of red blood cells and platelets

Thromb Haemost 2008; 100(05): 735
DOI: 10.1160/TH08-09-0584

Editorial Focus

Schattauer GmbH

Boris Shenkman

¹Amalia Biron Research Institute of Thrombosis and Hemostasis, Sheba Medical Center, Tel-Hashomer, Israel

References
1 Rund D, Rachmilewitz EA. Beta-thalassemia. N Engl J Med 2005; 353: 1135-1146.
2 Taher A, Isma’eel H, Mehio G. et al. Prevalence of thromboembolic events among 8860 patients with thalassemia major and intermedia in the Mediterranean area and Iran. Throm Haemost 2006; 96: 488-491.
3 Kohen R, Nyska A. Oxidation of biological systems: oxidative stress phenomena, antioxidants, Redox reactions, and methods for their quantification. Toxicol Pathol 2002; 30: 620-650.
4 Amer J, Fibach E. Oxidative status of platelets in normal and thalassemic blood. Thromb Haemost 2004; 92: 1052-1059.
5 Eldor A, Rachmilewitz EA. The hypercoagulable state in thalassemia. Blood 2002; 99: 36-43.
6 Goldschmidt N, Spectre G, Brill A. et al. Increased platelet adhesion under flow conditions is induced by both thalassemic platelets and red blood cells. Thromb Haemost 2008; 100: 864-870.
7 Shenkman B, Savion N, Dardik R. et al. Testing of platelet deposition on polystyrene surface under flow conditions by the cone and plate(let) analyzer: role of platelet activation, fibrinogen and von Willebrand factor. Thromb Res 2000; 99: 353-361.