Application of platelet function testing to the bedside

Craig D. Williams; Ganesh Cherala; Victor Serebruany

doi:10.1160/TH09-06-0375

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 2010; 103(01): 29-33
DOI: 10.1160/TH09-06-0375

Clinical Focus

Schattauer GmbH

Application of platelet function testing to the bedside

Craig D. Williams

¹Department of Pharmacy Practice, Oregon State University and Oregon Health and Science University College of Pharmacy, Portland, Oregon, USA

,

Ganesh Cherala

¹Department of Pharmacy Practice, Oregon State University and Oregon Health and Science University College of Pharmacy, Portland, Oregon, USA

,

Victor Serebruany

²HeartDrug Research, Johns Hopkins University, Towson, Maryland, USA

› Author Affiliations

Abstract

Summary

The ability to test platelet reactivity in clinical practice could help in making informed decisions on both initiation and titration of anti-platelet drug therapies. However, many barriers still remain to the effective implementation of such techniques. Many tests used in the research literature are not yet available for practical, clinical use. Platelet aggregometry, while informative and currently available for bedside use, needs additional research before routine clinical use can be recommended. This review will highlight and update contemporary issues of bedside platelet testing for the clinician and comment on future areas of clinical research.

Keywords

Clopidogrel - aspirin - platelet aggregation - platelet function tests - anti-platelet tests

Full Text

References

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