Fulminant arterial thrombosis leading to amputation of forearm in a 16-year-old girl – Disastrous combination of diabetes mellitus, factor V Leiden mutation and oral contraception

Christine Happle; Carolin Hartmann; Thomas Jack; Martin Boehne; Harald Bertram; Armin Wessel; Stephan Schoof

doi:10.1160/TH09-08-0537

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 2010; 103(05): 1104-1105
DOI: 10.1160/TH09-08-0537

Letters to the Editor

Schattauer GmbH

Fulminant arterial thrombosis leading to amputation of forearm in a 16-year-old girl – Disastrous combination of diabetes mellitus, factor V Leiden mutation and oral contraception

Authors

Christine Happle^*

¹Department of Pediatrics and Adolescent Medicine, Pediatric Cardiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany
Carolin Hartmann^*

¹Department of Pediatrics and Adolescent Medicine, Pediatric Cardiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany
Thomas Jack

¹Department of Pediatrics and Adolescent Medicine, Pediatric Cardiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany
Martin Boehne

¹Department of Pediatrics and Adolescent Medicine, Pediatric Cardiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany
Harald Bertram

¹Department of Pediatrics and Adolescent Medicine, Pediatric Cardiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany
Armin Wessel

¹Department of Pediatrics and Adolescent Medicine, Pediatric Cardiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany
Stephan Schoof

¹Department of Pediatrics and Adolescent Medicine, Pediatric Cardiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany

Abstract

Full Text

References

References
1 Monagle P, Newall F, Barnes C. et al. Arterial thromboembolic disease: a single-centre case series study. J Paediatr Child Health 2008; 44: 28-32.
2 Dorweiler B, Neufang A, Kasper-Koenig W. et al. Arterial embolism to the upper extremity in a patient with factor V Leiden mutation (APC resistance)-a case report and review of the literature. Angiology 2003; 54: 125-130.
3 Haller MJ, Valladares A, Rosenbloom AL. Arterial thrombosis resulting in amputation in a child with poorly controlled type 1 diabetes and heterozygous Factor V Leiden mutation. Pediatr Diabetes 2006; 07: 229-231.
4 Rosenbloom AL. Fatal cerebral infarctions in diabetic ketoacidosis in a child with previously unknown heterozygosity for factor V Leiden deficiency. J Pediatr 2004; 145: 561-562.
5 Carr ME. Diabetes mellitus: a hypercoagulable state. J Diabetes Complications 2001; 15: 44-54.
6 Nowak-Göttl U, Kosch A, Schlegel N. Thromboembolism in newborns, infants and children. Thromb Haemost 2001; 86: 464-474.
7 Kemmeren JM, Algra A, Meijers JC. et al. Effects of second and third generation oral contraceptives and their respective progestagens on the coagulation system in the absence or presence of the factor V Leiden mutation. Thromb Haemost 2002; 87: 199-205.
8 Slooter AJ, Rosendaal FR, Tanis BC. et al. Prothrombotic conditions, oral contraceptives, and the risk of ischemic stroke. J Thromb Haemost 2005; 03: 1213-1217.
9 Abdollahi M, Cushman M, Rosendaal F. Obesity: risk of venous thrombosis and the interaction with coagulation factor levels and oral contraceptive use. Thromb Haemost 2003; 89: 493-498.
10 Hirsch AT. et al. ACC/AHA 2005 Practice guidelines for the management of patients with peripheral arterial disease (lower extremity, renal, mesenteric, and abdominal aortic): a collaborative report from the American Association for Vascular Surgery/Society for Vascular Surgery, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, Society of Interventional Radiology, and the ACC/AHA Task Force on Practice Guidelines (Writing Committee to Develop Guidelines for the Management of Patients With Peripheral Arterial Disease): endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation; National Heart, Lung, and Blood Institute; Society for Vascular Nursing; TransAtlantic Inter-Society Consensus; and Vascular Disease Foundation. Circulation 2006; 113: 463-654.
11 Richardson M, Allen G, Monathan P. Thrombosis in children: current perspective and distinct challenges. Thromb Haemost 2002; 88: 900-911.