Management of Antithrombotic Therapy in Atrial Fibrillation Patients Presenting with Acute Coronary Syndrome and/or Undergoing Percutaneous Coronary Intervention/ Stenting

Gregory Y. H. Lip; Kurt Huber; Felicita Andreotti; Harald Arnesen; K. Juhani Airaksinen; Thomas Cuisset; Paulus Kirchhof; Francisco Marín

doi:10.1160/TH09-08-0580

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 2010; 103(01): 13-28
DOI: 10.1160/TH09-08-0580

Consensus Document

Schattauer GmbH

Management of Antithrombotic Therapy in Atrial Fibrillation Patients Presenting with Acute Coronary Syndrome and/or Undergoing Percutaneous Coronary Intervention/ Stenting

A Consensus Document of the European Society of Cardiology Working Group on Thrombosis, endorsed by the European Heart Rhythm Association [EHRA] and the European Association of Percutaneous Cardiovascular Interventions [EAPCI]

Gregory Y. H. Lip^*

¹University of Birmingham Centre for Cardiovascular Sciences, City Hospital, Birmingham, UK

,

Kurt Huber^**

²3^rd Department of Medicine, Cardiology and Emergency Medicine, Wilhelminen-hospital, Vienna, Austria

,

Felicita Andreotti^***

³Department of Cardiovascular Medicine, “A. Gemelli” University Hospital, Rome, Italy

,

Harald Arnesen^***

⁴Department of Cardiology, Oslo University Hospital, Ullevål, Oslo, Norway

,

K. Juhani Airaksinen^***

⁵Department of Medicine, Turku University Hospital, Turku, Finland

,

Thomas Cuisset^***

⁶Department of Cardiology, CHU Timone, Marseille, France

,

Paulus Kirchhof^***

⁷Department of Cardiology and Angiology, Universitätsklinikum Münster, Münster, Germany

,

Francisco Marín^***

⁸Department of Cardiology, Hospital Universitario Virgen de la Arrixaca, Ctra Madrid-Cartagena s/n, Murcia, Spain

› Author Affiliations

Abstract

Summary

There remains uncertainty over optimal antithrombotic management strategy for patients with atrial fibrillation (AF) presenting with an acute coronary syndrome and/or undergoing percutaneous coronary intervention/stenting. Clinicians need to balance the risk of stroke and thromboembolism against the risk of recurrent cardiac ischaemia and/ or stent thrombosis, and the risk of bleeding. This consensus document comprehensively reviews the published evidence and presents a consensus statement on a ‘best practice’ antithrombotic therapy guideline for the management of antithrombotic therapy in such AF patients.

Keywords

Arial fibrillation - antithrombotic therapy - acute coronary syndrome - percutaneous coronary intervention - stenting - warfarin

Full Text

References

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