Rivaroxaban and false positive lupus anticoagulant testing

• References

• 1 Pengo V, Tripodi A, Reber G. et al. Update of the guidelines for lupus anticoagulant detection. Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibody of the Scientific and Standard-isation Committee of the International Society on Thrombosis and Haemostasis. J Thromb Haemost 2009; 7: 1737-1740.
• 2 Greaves M, Cohen H, MacHin SJ. et al. Guidelines on the investigation and management of the anti-phospholipid syndrome. Br J Haematol 2000; 109: 704-715.
• 3 Tripodi A. Testing for lupus anticoagulants: all that a clinician should know. Lupus 2009; 18: 291-298.
• 4 Genzen JR, Miller JL. Presence of direct thrombin inhibitors can affect the results and interpretation of lupus anticoagulant testing. Am J Clin Pathol 2005; 124: 586-593.
• 5 Gosselin RC, King JH, Janatpur KA. et al. Effects of pentasaccharide (fondaparinux) and direct thrombin inhibitors on coagulation testing. Arch Pathol Lab Med 2004; 128: 1142-1145.
• 6 Lambert M, Ferrard-Sasson G, Dubucquoi S. et al. Diluted Russell viper-venom time improves identification of antiphospholipid syndrome in a lupus anticoagulant-positive patient population. Thromb Haemost 2009; 101: 577-581.
• 7 Samama MM, Martinoli JL, LeFlem L. et al. Assessment of laboratory assays to measure rivaroxaban – an oral, direct factor Xa inhibitor. Thromb Haemost 2010; 103: 815-825.