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Thromb Haemost 2011; 106(02): 381-382
DOI: 10.1160/TH11-03-0191
DOI: 10.1160/TH11-03-0191
Letters to the Editor
Massive muscle haematoma three months after starting vitamin K antagonist therapy for deep-vein thrombosis in an antithrombin deficient patient: Another case of factor IX propeptide mutation
Further Information
Publication History
Received: 22 March 2011
Accepted after major revision: 12 May 2011
Publication Date:
25 November 2017 (online)
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References
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- 3 Luxembourg B, Delev D, Geisen C. et al. Molecular basis of antithrombin deficiency. Thromb Haemost 2011; 105: 635-646.
- 4 Oldenburg J, Quenzel EM, Harbrecht U. et al. Missense mutations at ALA-10 in the factor IX propeptide: an insignificant variant in normal life but a decisive cause of bleeding during oral anticoagulant therapy. Br J Haematol 1997; 98: 240-244.
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- 8 van der Heijden JF, Rekke B, Hutten BA. et al. Nonfatal major bleeding during treatment with vitamin K antagonists: influence of soluble thrombomodulin and mutations in the propeptide of coagulation factor IX. J Thromb Haemost 2004; 2: 1104-1109.
- 9 Aegerter C, Fontana S, Fux C. et al. Life threatening bleeding under adequate oral anticoagulation. Hamostaseologie 2003; 23: 113-116.
- 10 Ulrich S, Brand B, Speich R. et al. Congenital hypersensitivity to vitamin K antagonists due to FIX propeptide mutation at locus -10: a (not so) rare cause of bleeding under oral anticoagulant therapy in Switzerland. Swiss Med Wkly 2008; 138: 100-107.
- 11 Holbro A, Marbet GA, Tran TH. et al. Prosthetic heart valves and rare hypersensitivity to vitamin K antagonists resulting from factor IX mutation: how to manage anticoagulation?. Haemophilia 2010; 1: 187-189.