Download PDF
Thromb Haemost 2013; 109(01): 5-6
DOI: 10.1160/TH12-11-0817
Invited Editorial Focus
Schattauer GmbH

Platelet microparticles: reinforcing the hegemony of platelets in atherothrombosis

Sebastian F. Mause
1   Department of Cardiology, Medical Faculty, RWTH Aachen University, Aachen, Germany
› Author Affiliations
Further Information

Publication History

Received: 12 November 2012

Accepted: 12 November 2012

Publication Date:
25 November 2017 (online)

Also available at
    Permissions and Reprints

Editorial on: Suades et al. Thromb Haemost 2012; 108: 1208-1219.

 

  • References

  • 1 VanWijk MJ, VanBavel E, Sturk A. et al. Microparticles in cardiovascular diseases. Cardiovasc Res 2003; 59: 277-287. DOI:10.1016/S0008-6363(03)00367-5.
    CrossrefPubMedGoogle Scholar
  • 2 Burnier L, Fontana P, Kwak BR. et al. Cell-derived microparticles in haemostasis and vascular medicine. Thromb Haemost 2009; 101: 439-451.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 3 Mause SF, von Hundelshausen P, Zernecke A. et al. Platelet microparticles: a transcellular delivery system for RANTES promoting monocyte recruitment on endothelium. Arterioscler Thromb Vasc Biol 2005; 25: 1512-1518. DOI:10.1161/01.ATV.0000170133.43608.37.
    CrossrefPubMedGoogle Scholar
  • 4 Namba M, Tanaka A, Shimada K. et al. Circulating platelet-derived microparticles are associated with atherothrombotic events: a marker for vulnerable blood. Arterioscl Thromb Vasc Biol 2007; 27: 255-256. DOI:10.1161/01.ATV.0000252064.97632.2c.
    CrossrefPubMedGoogle Scholar
  • 5 Mause SF, Weber C. Microparticles: protagonists of a novel communication network for intercellular information exchange. Circ Res 2010; 107: 1047-1057. DOI:10.1161/CIRCRESAHA.110.226456.
    CrossrefPubMedGoogle Scholar
  • 6 Mause SF, Ritzel E, Liehn EA. et al. Platelet microparticles enhance the vasoregenerative potential of angiogenic early outgrowth cells after vascular injury. Circulation 2010; 122: 495-506. DOI:10.1161/CIRCULATIONAHA.109.909473.
    CrossrefPubMedGoogle Scholar
  • 7 Morel O, Toti F, Hugel B. et al. Procoagulant microparticles: disrupting the vascular homeostasis equation?. Arterioscler Thromb Vasc Biol 2006; 26: 2594-2604. DOI:10.1161/01.ATV.0000246775.14471.26.
    CrossrefPubMedGoogle Scholar
  • 8 Sinauridze EI, Kireev DA, Popenko NY. et al. Platelet microparticle membranes have 50- to 100-fold higher specific procoagulant activity than activated platelets. Thromb Haemost 2007; 97: 425-434.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 9 Hrachovinová I, Cambien B, Hafezi-Moghadam A. et al. Interaction of P-selectin and PSGL-1 generates microparticles that correct hemostasis in a mouse model of hemophilia A. Nat Med 2003; 09: 1020-1025. DOI:10.1038/nm899.
    CrossrefPubMedGoogle Scholar
  • 10 Rautou PE, Vion AC, Amabile N. et al. Microparticles, vascular function, and atherothrombosis. Circ Res 2011; 109: 593-606. DOI:10.1161/CIRCRESAHA.110.233163.
    CrossrefPubMedGoogle Scholar
  • 11 Owens 3rd AP, Mackman N. Microparticles in hemostasis and thrombosis. Circ Res 2011; 108: 1284-1297. DOI:10.1161/CIRCRESAHA.110.233056.
    CrossrefPubMedGoogle Scholar
  • 12 Giesen PL, Rauch U, Bohrmann B. et al. Blood-borne tissue factor: another view of thrombosis. Proc Natl Acad Sci USA 1999; 96: 2311-2315. DOI:10.1073/pnas.96.5.2311.
    CrossrefPubMedGoogle Scholar
  • 13 Zwicker JI, Trenor 3rd CC, Furie BC. et al. Tissue factor-bearing microparticles and thrombus formation. Arterioscler Thromb Vasc Biol 2011; 31: 728-733. DOI:10.1161/ATVBAHA.109.200964.
    CrossrefPubMedGoogle Scholar
  • 14 Suades R, Padró T, Vilahur G. et al. Circulating and platelet-derived microparticles in human blood enhance thrombosis on atherosclerotic plaques. Thromb Haemost 2012; 108: 1208-1219. DOI:10.1160/TH12-07-0486.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 15 Naghavi M, Libby P, Falk E. et al. From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I. Circulation 2003; 108: 1664-1672. DOI:10.1161/01.CIR.0000087480.94275.97.
    CrossrefPubMedGoogle Scholar
  • 16 Namba M, Tanaka A, Shimada K. et al. Circulating platelet-derived microparticles are associated with atherothrombotic events: a marker for vulnerable blood. Arterioscler Thromb Vasc Biol 2007; 27: 255-256. DOI:10.1161/01.ATV.0000252064.97632.2c.
    CrossrefPubMedGoogle Scholar