Thrombosis and Haemostasis, Table of Contents Thromb Haemost 2013; 109(05): 582DOI: 10.1160/TH13-03-0235 Invited Editorial Focus Schattauer GmbH On elucidating a possible link between vitamin D and venous thromboembolism – Finding a piece of the puzzle Pelle G. Lindqvist Recommend Article Abstract Buy Article Full Text References References 1 Lindqvist PG, Epstein E, Olsson H. The relationship between lifestyle factors and venous thromboembolism among women: a report from the MISS study. Br J Haematol 2009; 144: 234-240. 2 Lindqvist PG, Bremme K, Hellgren M. Efficacy of obstetric thromboprophylaxis and long-term risk of recurrence of venous thromboembolism. Acta Obstet Gynecol Scand 2011; 90: 648-653. 3 Schulman S, Rhedin AS, Lindmarker P. et al. A comparison of six weeks with six months of oral anticoagulant therapy after a first episode of venous thromboembolism. Duration of Anticoagu-lation Trial Study Group. N Engl J Med 1995; 332: 1661-1665. 4 Rodger MA, Kahn SR, Wells PS. et al. Identifying unprovoked thromboembolism patients at low risk for recurrence who can discontinue anticoagulant therapy. Cmaj 2008; 179: 417-426. 5 Brodin E, Lerstad G, Grimnes G. et al. Serum levels of vitamin D are not associated with future risk of venous thromboembolism. The Tromso Study. Thromb Haemost 2013; 109: 885-890. 6 Boulay F, Berthier F, Schoukroun G. et al. Seasonal variations in hospital admission for deep vein thrombosis and pulmonary embolism: analysis of discharge data. Br Med J 2001; 323: 601-602. 7 Bounameaux H, Hicklin L, Desmarais S. Seasonal variation in deep vein thrombosis. Br Med J 1996; 312: 284-285. 8 Manfredini R, Boari B, Salmi R. et al. Seasonal variation of venous thromboembolic disease. Am J Cardiol 2004; 94: 276. 9 Lindqvist PG, Epstein E, Olsson H. Does an active sun exposure habit lower the risk of venous thrombotic events? A D-lightful hypothesis. J Thromb Haemost 2009; 07: 605-610. 10 Brot C, Vestergaard P, Kolthoff N. et al. Vitamin D status and its adequacy in healthy Danish perime-nopausal women: relationships to dietary intake, sun exposure and serum parathyroid hormone. Br J Nutr 2001; 86 (Suppl. 01) S97-103. 11 Hypponen E, Berry D, Cortina-Borja M. et al. 25-Hydroxyvitamin D and pre-clinical alterations in inflammatory and hemostatic markers: a cross sectional analysis in the 1958 British Birth Cohort. PLoS ONE 2010; 05: e10801. 12 Naess IA, Christiansen SC, Romundstad P. et al. Incidence and mortality of venous thrombosis: a population-based study. J Thromb Haemost 2007; 05: 692-699. 13 Enga KF, Braekkan SK, Hansen-Krone IJ. et al. Cigarette smoking and the risk of venous thromboembolism: the Tromso Study. J Thromb Haemost 2012; 10: 2068-2074. 14 Blondon M, Wiggins KL, McKnight B. et al. The association of smoking with venous thrombosis in women. A population-based, case-control study. Thromb Haemost 2013; 109: 891-896. 15 Hansen-Krone IJ, Braekkan SK, Enga KF. et al. Alcohol consumption, types of alcoholic beverages and risk of venous thromboembolism - the Tromso Study. Thromb Haemost 2011; 106: 272-278. 16 Enga KF, Braekkan SK, Hansen-Krone IJ. et al. Coffee consumption and the risk of venous thromboembolism: the Tromso study. J Thromb Haemost 2011; 09: 1334-1339. 17 Lindqvist PG, Dahlback B. Reactions to awareness of activated protein C resistance carriership: a descriptive study of 270 women. Acta Obstet Gynecol Scand 2003; 82: 467-470. 18 Koyama T, Shibakura M, Ohsawa M. et al. Anticoagulant effects of 1alpha,25-dihydroxyvitamin D3 on human myelogenous leukemia cells and monocytes. Blood 1998; 92: 160-167. 19 Asakura H, Aoshima K, Suga Y. et al. Beneficial effect of the active form of vitamin D3 against LPS-induced DIC but not against tissue-factor-induced DIC in rat models. Thromb Haemost 2001; 85: 287-290. 20 Kebapcilar AG, Kulaksizoglu M, Ipekci SH. et al. Relationship between mean platelet volume and low-grade systemic coagulation with vitamin D deficiency in primary ovarian insufficiency. Arch Gynecol Obstet. 2013 Epub ahead of print 21 Clemens TL, Adams JS, Henderson SL. et al. Increased skin pigment reduces the capacity of skin to synthesise vitamin D3. Lancet 1982; 01: 74-76. 22 Tsai AW, Cushman M, Rosamond WD. et al. Cardiovascular risk factors and venous thromboembolism incidence: the longitudinal investigation of thromboembolism etiology. Arch Intern Med 2002; 162: 1182-1189. 23 Holick MF. Vitamin D deficiency. N Engl J Med 2007; 357: 266-281.