Thromb Haemost 2014; 111(06): 1177-1179
DOI: 10.1160/TH13-09-0746
Letters to the Editor
Schattauer GmbH

Immature platelet fraction analysis demonstrates a difference in thrombopoiesis between normotensive and preeclamptic pregnancies

Thomas R. Everett
1   Fetal Medicine Department, Rosie Hospital, Addenbrooke’s Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
,
Stephen F. Garner
2   Department of Haematology, University of Cambridge, Cambridge, UK
3   National Health Service Blood and Transplant, Cambridge, CB2 OPT, UK
,
Christoph C. Lees
4   Centre for Fetal Care, Queen Charlotte’s and Chelsea Hospital, Imperial Healthcare NHS Trust, London, UK
5   Department of Development and Regeneration, University Hospitals Leuven, Campus Gasthuisberg, Leuven, Belgium
,
Alison H. Goodall
6   Department of Cardiovascular Sciences, University of Leicester and NIHR Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK
› Institutsangaben
Financial support: TRE was funded by a grant from the Evelyn Trust. The study was supported in part by program grants from the National Institute for Health Research (NIHR, RPPG-0310-1002) and NIHR Cambridge Biomedical Research Centre funding to the National Health Service Blood and Transplant Cambridge BioResource.
Weitere Informationen

Publikationsverlauf

Received: 10. September 2013

Accepted after major revision: 20. Januar 2013

Publikationsdatum:
02. Dezember 2017 (online)

 

 
  • References

  • 1 Janes SL, Goodall AH. Flow cytometric detection of circulating activated platelets and platelet hyper-responsiveness in pre-eclampsia and pregnancy. Clin Sci 1994; 86: 731-739.
  • 2 Boehlen F, Hohlfeld P, Extermann P. et al. Platelet count at term pregnancy: a reappraisal of the threshold. Obstet Gynecol 2000; 95: 29-33.
  • 3 Fay RA, Hughes AO, Farron NT. Platelets in pregnancy: hyperdestruction in pregnancy. Obstet Gynecol 1983; 61: 238-240.
  • 4 Wallenburg H, Kessel PH. Platelet lifespan in normal pregnancy as determined by a nonradioisotopic technique. Br J Obstet Gynecol 1978; 85: 33-36.
  • 5 Schulze H, Shivdasani RA. Mechanisms of thrombopoiesis. J Thromb Haemost 2005; 03: 1717-1724.
  • 6 Briggs C, Kunka S, Hart D. et al. Assessment of an immature platelet fraction (IPF) in peripheral thrombocytopenia. Br J Haematol 2004; 126: 93-99.
  • 7 Harrison P, Goodall AH. ‘Message in the pla-telet’--more than just vestigial mRNA! Platelets. 2008; 19: 395-404.
  • 8 Abe Y, Wada H, Tomatsu H. et al. A simple technique to determine thrombopoiesis level using immature platelet fraction (IPF). Thromb Res 2006; 118: 463-469.
  • 9 Briggs C, Harrison P, Machin SJ. Continuing developments with the automated platelet count. Int J Lab Hematol 2007; 29: 77-91.
  • 10 Briggs C, Hart D, Kunka S. et al. Immature platelet fraction measurement: a future guide to platelet transfusion requirement after haematopoietic stem cell transplantation. Transfus Med 2006; 16: 101-109.
  • 11 National Institute for Health and Care Excellence (2010) Hypertension in Pregnancy. CG107. London: National Institute for Health and Care Excellence.
  • 12 Kickler TS, Oguni S, Borowitz MJ. A clinical evaluation of high fluorescent platelet fraction percentage in thrombocytopenia. Am J Clin Pathol 2006; 125: 282-287.
  • 13 Lees CC, Brown AS, Harrington KF. et al. A cross-sectional study of platelet volume in healthy normotensive women with bilateral uterine artery notches. Ultrasound Obstet Gynecol 1997; 10: 277-281.
  • 14 Kazmi R, Cooper A, Lwaleed B. Platelet Function in Pre-Eclampsia. Semin Thromb Hemost 2011; 37: 131-136.
  • 15 Rinder HM, Bonan JL, Anandan S. et al. Nonin-vasive measurement of platelet kinetics in normal and hypertensive pregnancies. Am J Obstet Gynecol 1994; 170: 117-122.
  • 16 Zucker ML, Murphy CA, Rachel JM. et al. Immature platelet fraction as a predictor of platelet recovery following hematopoietic progenitor cell transplantation. Lab Hematol 2006; 12: 125-130.
  • 17 Altınbas S, Toğrul C, Orhan A. et al. Increased MPV is not a significant predictor for preeclampsia during pregnancy. J Clin Lab Anal 2012; 26: 403-406.