Thromb Haemost 2014; 112(04): 629
DOI: 10.1160/TH14-09-0734
T&H Insights
Schattauer GmbH

LDL-receptor-deficient mice lacking microRNA-143/145 have less atherosclerosis

Aitana Braza-BoÏls
1   Grupo de Hemostasia, Trombosis, Arteriosclerosis y Biología Vascular, Instituto Investigación Sanitaria,Hospital La Fe (IIS La Fe), Valencia, Spain
2   King’s British Heart Foundation Centre, King’s College London, London, UK
,
Manuel Mayr
2   King’s British Heart Foundation Centre, King’s College London, London, UK
› Author Affiliations
Further Information

Publication History

Received: 05 September 2014

Accepted: 05 September 2014

Publication Date:
20 November 2017 (online)

Insight on: Sala et al. Thromb Haemost 2014; 112: 796-802.

 
  • References

  • 1 Boettger T, Beetz N, Kostin S. et al. Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster. J Clin Invest 2009; 119: 2634-2647.
  • 2 Sala F, Aranda JF, Rotllan N. et al. MiR-143/145 deficiency protects against progression of atherosclerosis in Ldlr-/-mice. Thromb Haemost 2014; 112: 796-802.
  • 3 Hergenreider E, Heydt S, Tréguer K. et al. Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs. Nat Cell Biol 2012; 14: 249-256.