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Thromb Haemost 2017; 117(01): 196-197
DOI: 10.1160/TH16-06-0445
DOI: 10.1160/TH16-06-0445
Letters to the Editor
Idarucizumab administration for reversing dabigatran effect in an acute kidney injured patient with bleeding
Further Information
Publication History
Received:
10 June 2016
Accepted after major revision:
20 September 2016
Publication Date:
01 December 2017 (online)
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References
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- 3 Connolly SJ, Ezekowitz MD, Yusuf S. et al. RE-LY Steering Committee and Investigators. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med 2009; 361: 1139-1151.
- 4 Miyares MA, Kuyumjian Y, Eaves S, Dollard E. Idarucizumab, a Humanized, Monoclonal Antibody Fragment for Immediate Reversal of Dabigatran. J Pharm Pract 2015; 28: 548-554.
- 5 Glund S, Stangier J, Schmohl M. et al. Safety, tolerability, and efficacy of Idarucizumab for the reversal of the anticoagulant effect of dabigatran in healthy male volunteers: a randomised, placebo-controlled, double-blind phase 1 trial. Lancet 2015; 386: 680-690.
- 6 Glund S, Moschetti V, Norris S. et al. A randomised study in healthy volunteers to investigate the safety, tolerability and pharmacokinetics of Idarucizumab, a specific antidote to dabigatran. Thromb Haemost 2015; 113: 943-951.
- 7 Pollack CV, Reilly PA, Eikelboom J. et al. Idarucizumab for Dabigatran Reversal. N Engl J Med 2015; 373: 511-520.