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CC BY 4.0 · Aorta (Stamford) 2015; 03(01): 9-15
DOI: 10.12945/j.aorta.2015.14-041
State-of-the-Art Review
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Expanding Horizons for Abdominal Aortic Aneurysms

Rachel C. Rolph
1   King’s College London, BHF Centre of Research Excellence & NIHR Biomedical Research Centre at King’s Health Partners, Academic Department of Surgery, Cardiovascular Division and Division of Imaging Sciences, St Thomas’ Hospital, London, UK
,
Matthew Waltham
1   King’s College London, BHF Centre of Research Excellence & NIHR Biomedical Research Centre at King’s Health Partners, Academic Department of Surgery, Cardiovascular Division and Division of Imaging Sciences, St Thomas’ Hospital, London, UK
,
Alberto Smith
1   King’s College London, BHF Centre of Research Excellence & NIHR Biomedical Research Centre at King’s Health Partners, Academic Department of Surgery, Cardiovascular Division and Division of Imaging Sciences, St Thomas’ Hospital, London, UK
,
Helena Kuivaniemi
2   The Sigfried and Janet Weis Center for Research, Geisinger Health System, Danville, Pennsylvania, USA
3   Department of Surgery, Temple University School of Medicine, Philadelphia, Pennsylvania, USA
› Author Affiliations
Further Information

Publication History

15 July 2014

29 September 2014

Publication Date:
24 September 2018 (online)

Also available at
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Abstract

Recent technological advances have allowed researchers to interrogate the genetic basis of abdominal aortic aneurysms in great detail. The results from these studies are expected to transform our understanding of this complex disease with both multiple genetic and environmental risk factors. Clinicians need to keep abreast of these genetic findings and understand the implications for their practice. Patients will become increasingly informed on genetic risk, and a new era of individualized risk assessment for AAA is just beginning. This brief update aims to provide the clinician with a succinct précis of the recent progress in this area.

Key Words

Genetic - Association Studies - Risk score - Aneurysm - DNA Sequencing
 

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