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CC BY 4.0 · Aorta (Stamford) 2016; 04(01): 25-28
DOI: 10.12945/j.aorta.2015.15.009
DOI: 10.12945/j.aorta.2015.15.009
Case Report
Complete Resolution of Wegener’s Granulomatosis Lung Granuloma After Aortic Root Replacement
Further Information
Publication History
22 March 2015
19 October 2015
Publication Date:
24 September 2018 (online)
![](https://www.thieme-connect.de/media/10.1055-s-00039245/201601/lookinside/thumbnails/10-12945-j-aorta-2015-15-009_04009-1.jpg)
Abstract
Wegner’s granulomatosis (WG) is an autoimmune systemic vasculitis that results in necrotizing granulomas. We report a WG patient with a lung granuloma and aortic root dilatation, who underwent aortic root replacement on cardiopulmonary bypass (CPB). Intraoperatively, the patient suffered an aortic dissection, which was repaired immediately under deep hypothermic circulatory arrest (DHCA). Follow-up imaging showed complete granuloma resolution, despite absence of immunosuppressive therapy. Immune stimulation following CPB is well described; here, the opposite was observed and DHCA effects are discussed.
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