Leishmania-infantum-bedingte Knochenläsionen bei einem Hund

Zusammenfassung

Ein aus Spanien stammender, 3-jähriger Labrador-Retriever-Rüde wurde aufgrund einer seit mehreren Monaten bestehenden Lahmheit der linken Hintergliedmaße vorgestellt. Die orthopädische Untersuchung ergab eine Schmerzhaftigkeit bei Manipulation des linken Tarsus. Röntgenologisch und computertomographisch ließen sich polyostotische, aggressive osteolytische Knochenläsionen mit beginnender erosiver Arthritis nachweisen. Durch Untersuchung eines Knochenbioptats mittels PCR konnte über einen direkten Erregernachweis die Diagnose Leishmaniose gestellt werden. Drei Wochen nach Beginn einer Behandlung mit Allopurinol war der Hund lahmheitsfrei. Acht Monate nach Therapiebeginn zeigte sich röntgenologisch eine mittelgradige Regression der Osteolysen.

Summary

A 3-year-old Labrador Retriever originating from Spain was presented with a left-sided hind limb lameness for several months. The orthopedic examination revealed a pain response when palpating the left tarsal joint. Radiographic and computed tomographic studies showed polyostotic, aggressive osteolytic bone lesions with mild erosive arthritis. The diagnosis of canine leishmaniasis was confirmed by bone biopsy and the detection of the pathogen by PCR. Three weeks after initiation of therapy with allopurinol, the dog presented no signs of lameness. Eight months after start of therapy, radiographic examina - tion revealed moderate regression of the osteolytic bone lesions.

Schlüsselwörter

Leishmaniose - Lahmheit - Osteolyse - Röntgen - Computertomographie - Allopurinol

Keywords

Leishmaniasis - lameness - osteolysis - radiography - computed tomogra - phy - allopurinol

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