Aktuelle Kenntnisse zu Therapie und Prävention der kaninen Leishmaniose

Neoklis Apostolopoulos; Athanasia Mitropoulou; Nina Thom; Andreas Moritz

doi:10.15654/TPK-180089

Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere, Table of Contents

Tierarztl Prax Ausg K Kleintiere Heimtiere 2018; 46(05): 315-322
DOI: 10.15654/TPK-180089

Übersichtsartikel – Review Article

Georg Thieme Verlag KG Stuttgart · New York

Aktuelle Kenntnisse zu Therapie und Prävention der kaninen Leishmaniose

Article in several languages: deutsch | English

Neoklis Apostolopoulos

¹AniCura Kleintierspezialisten Augsburg GmbH, Augsburg

,

Athanasia Mitropoulou

²Klinik für Kleintiere – Innere Medizin, Justus-Liebig-Universität Gießen

,

Nina Thom

²Klinik für Kleintiere – Innere Medizin, Justus-Liebig-Universität Gießen

,

Andreas Moritz

²Klinik für Kleintiere – Innere Medizin, Justus-Liebig-Universität Gießen

› Author Affiliations

Abstract

Zusammenfassung

Die kanine Leishmaniose ist eine Infektionskrankheit, die zunehmend an Bedeutung gewinnt, da auch in Deutschland der Hauptvektor der Leishmaniose vorkommt und Einzelfälle autochthoner Infektionen beschrieben sind. Der Artikel fasst aktuelle Informationen über Therapie und Prävention der Leishmaniose zusammen. Kürzlich wurden bei Hunden, die unter Allopurinoltherapie ein Rezidiv der Erkrankung erlitten, Allopurinol-resistente Leishmania-infantum-Stämme gefunden. Daher werden alternative Langzeittherapien erforderlich. Auch die Ergebnisse aus Langzeitstudien zur Effizienz von Miltefosin im Vergleich zu Megluminantimonat können die Wahl des leishmaniziden Therapeutikums beeinflussen. Eine Vielzahl verschiedener Repellenzien steht zur Übertragungsprophylaxe zur Verfügung. In Europa sind zwei Impfstoffe für Hunde zugelassen, um das Risiko einer aktiven Infektion und den Schweregrad der klinischen Erkrankung zu reduzieren.

Schlüsselwörter

Diätetische Nukleotide - AHCC - Resistenz - Impfung - LetiFend® - Cani-Leish®

Full Text

References

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