Primary central nervous system tumors in Sergipe, Brazil: descriptive epidemiology between 2010 and 2018

ABSTRACT

Background: Central nervous system (CNS) tumors are a heterogeneous group with high morbidity and mortality. Objectives: To describe the epidemiology of primary CNS tumors diagnosed in the state of Sergipe from 2010 to 2018. Methods: We evaluated histopathological and immunohistochemical reports on primary CNS tumors diagnosed in Sergipe, Brazil, between 2010 and 2018 and collected data regarding age, sex, location, World Health Organization (WHO) classification and histology. Results: Altogether, 861 primary CNS tumors were found. Tumors in brain locations occurred most frequently (50.8%; n=437). The neoplasms observed were most prevalent in the age range 45–54 years (20.4%; n=176). Grade I tumors occurred most frequently, corresponding to 38.8% of the cases (n=38) in the age group of 0–14 years, and 44.6% (n=340) in the population ≥15 years old. Between 0 and 14 years of age, other astrocytic tumors were the most prevalent (29.6%; n=29). In the age group between 15 and 34, gliomas were the most frequent (32.7%; n=54). Meningiomas predominated in the age group of 35 years and above, comprising 47.5% of cases (n=206) in the 35–74 age group; and 61.2% (n=30) among patients over 75 years old. Conclusion: The epidemiology of primary CNS tumors in Sergipe between 2010 and 2018 is consistent with data in other current studies on the subject. Studies on the epidemiological evolution of these entities in Sergipe are needed.

RESUMO

Introdução: Os tumores do sistema nervoso central (SNC) são um grupo heterogêneo de entidades que apresenta significativa morbimortalidade. Objetivos: O presente estudo visa à descrição epidemiológica dos tumores primários do SNC com diagnóstico histopatológico no estado de Sergipe, Brasil, entre 2010 e 2018. Métodos: Foram avaliados laudos histopatológicos e imuno-histoquímicos de tumores primários do SNC, diagnosticados entre 2010 e 2018, no estado de Sergipe. Os dados coletados foram descritos de acordo com as variáveis de idade, sexo, localização, classificação da Organização Mundial da Saúde (OMS) e tipo histológico. Resultados: Foram encontrados 861 tumores primários do SNC. A localização cerebral foi a mais frequente (50,8%; n=437). As neoplasias observadas prevaleceram na faixa etária de 45 a 54 anos (20,4%; n=176). Os tumores grau I foram os mais frequentes, correspondendo a 38,8% dos casos (n=38) na faixa etária de 0–14 anos e 44,6% (n=340) na população a partir de 15 anos de idade. Na faixa etária entre 0–14 anos, o grupo histológico dos outros tumores astrocíticos foi o mais prevalente (29,6%; n=29). Na população entre 15–34 anos, os gliomas foram os mais frequentes (32,7%; n=54). Os meningiomas predominaram nas faixas etárias a partir de 35 anos, com 47,5% dos casos (n=206) entre 35–74 anos; e 61,2% (n=30) nos pacientes acima de 75 anos de idade. Conclusão: A descrição epidemiológica dos tumores primários do SNC em Sergipe, entre 2010 e 2018, é condizente com outros trabalhos atuais sobre o tema. Estudos voltados à evolução epidemiológica dessas entidades em Sergipe são necessários.

Keywords:

Brain Neoplasms - Epidemiology - Prevalence

Palavras-chave:

Neoplasias Encefálicas - Epidemiologia - Prevalência

Authors’ contributions:

HAO and AMPO: study conception and design. BLS and HAO: acquisition of data. BLS and AMPO: analysis and interpretation of data. BLS, AMPO and RLOA: writing of the manuscript. BLS and RLOA: critical review.

Publication History

Received: 08 April 2020

Accepted: 21 October 2020

Article published online:
04 July 2023

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