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CC BY-NC-ND 4.0 · Arq Neuropsiquiatr 2021; 79(05): 457-459
DOI: 10.1590/0004-282X-ANP-2020-0406
Historical Notes

Abnormal eye movements in parkinsonism: a historical view

Movimentos oculares anormais em parkinsonismo: uma visão histórica
Tereza Ko 
1   Universidade Federal de Ciências da Saúde de Porto Alegre, Faculdade de Medicina, Porto Alegre RS, Brazil.
,
Augusto Mädke Brenner 
1   Universidade Federal de Ciências da Saúde de Porto Alegre, Faculdade de Medicina, Porto Alegre RS, Brazil.
,
Nicholas Pili Monteiro 
1   Universidade Federal de Ciências da Saúde de Porto Alegre, Faculdade de Medicina, Porto Alegre RS, Brazil.
,
Mariana Severo Debastiani 
1   Universidade Federal de Ciências da Saúde de Porto Alegre, Faculdade de Medicina, Porto Alegre RS, Brazil.
,
Alberto Chitolina Nesello 
1   Universidade Federal de Ciências da Saúde de Porto Alegre, Faculdade de Medicina, Porto Alegre RS, Brazil.
,
Arlete Hilbig 
2   Universidade Federal de Ciências da Saúde de Porto Alegre, Departamento de Clínica Médica, Porto Alegre RS, Brazil.
3   Irmandade Santa Casa da Misericórdia de Porto Alegre, Serviço de Neurologia, Porto Alegre RS, Brazil.
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ABSTRACT

Parkinson's disease (PD), known since ancient times as paralysis agitans, was studied and described by James Parkinson in 1817 in his work “An Essay on the Shaking Palsy”. Fifty years later, Charcot and his students delved into the disease, naming it as we know it today, as well as defining the classic disease and its variants. One of these students, Arthur Dutil, addressed patients’ abnormal eye movements. Nowadays, it is known that the differential diagnosis of PD is relevant for prognosis, treatment and research, and, despite the advances in the area, it remains largely clinical. The relevance of the eye movement exam has grown along with the history of PD and it has proved to be an excellent tool for the differential diagnosis of parkinsonism. Additionally, it can become a support to identify different types of genetic PD and be useful for improving early recognition of cognitive decline in patients with PD.

RESUMO

A doença de Parkinson (DP), conhecida desde a antiguidade como paralysis agitans, foi estudada e descrita por James Parkinson em 1817 em seu trabalho An Essay on the Shaking Palsy. Cinquenta anos depois, Charcot e seus alunos aprofundaram os estudos na doença, nomeando-a como a conhecemos atualmente, bem como definindo a doença clássica e suas variantes. Um desses estudantes, Arthur Dutil, investigou os movimentos oculares anormais nos pacientes. Hoje, sabe-se que o diagnóstico diferencial da DP é relevante para o prognóstico, tratamento e pesquisa, e, apesar dos grandes avanços na área, ainda permanece amplamente clínico. A relevância do exame de movimentação ocular cresceu com a história da DP e este se mostrou uma excelente ferramenta para o diagnóstico diferencial do parkinsonismo. Além disso, pode se tornar um auxílio para identificar diferentes formas de DP genética e útil para melhorar o reconhecimento precoce do declínio cognitivo em pacientes com DP.

Keywords:

Eye Movements - History of Medicine - Parkinson Disease - Parkinsonian Disorders

Palavras-chave:

Movimentos Oculares - História da Medicina - Doença de Parkinson - Transtornos Parkinsonianos

Authors’ contributions:

TK: conceptualization, data curation, investigation, methodology, project administration, writing-original draft, writing-review & editing. AMB, NPM, MSD, ACN: conceptualization, data curation, investigation, methodology, writing-original draft, writing-review & editing. AH: conceptualization, data curation, investigation, methodology, project administration, supervision, validation, visualization, writing-original draft, writing-review & editing.




Publication History

Received: 24 August 2020

Accepted: 13 October 2020

Article published online:
07 June 2023

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