From REM to orexin: clinical progress in narcolepsy - was it worth the wait? was it worth the “weight?”

Kenneth Clayton Sassower

doi:10.1590/0004-282X-anp-2021-E009

Arquivos de Neuro-Psiquiatria, Table of Contents

CC BY-NC-ND 4.0 · Arq Neuropsiquiatr 2021; 79(09): 757-758
DOI: 10.1590/0004-282X-anp-2021-E009

Editorial

From REM to orexin: clinical progress in narcolepsy - was it worth the wait? was it worth the “weight?”

Do sono REM à orexina: evolução clínica em narcolepsia - valeu a pena a espera? Valeu a pena o “peso”?

Kenneth Clayton Sassower

¹Massachusetts General Hospital, Division of Sleep Medicine, Boston, Massachusetts, USA.

²Massachusetts General Hospital, Division of Clinical Neurophysiology, Boston, Massachusetts, USA.

› Author Affiliations

Abstract

Full Text

References

REFERENCES
1 Lennox WC. Thomas Willis on Narcolepsy. Arch Neur Psych. 1939 Feb;41(2):348-51. https://doi.org/10.1001/archneurpsyc.1939.02270140134010
2 Gelineau J. De la narcolepsie. Gazette des Hopitaux Civils et Militaires1880;53:626-8(Part a); 54:635-7(Part b).
3 Gowers WR. Borderland of Epilepsy. Philadelphia (US): Blakiston; 1907.
4 Wilson SAK. The narcolepsies. Brain. 1928 Mar;51:63-109. https://psycnet.apa.org/doi/10.1093/brain/51.1.63
5 Yoss RE, Daly DD. Criteria for the diagnosis of the narcoleptic syndrome. Proc Staff Meeting Mayo Clinic. 1957 Jun;32(12):320-8.
6 Vogel G. Studies in the psychophysiology of dreams III. The dream of narcolepsy. Arch Gen Psychiat. 1960 Oct;3:421-8. https://doi.org/10.1001/archpsyc.1960.01710040091011
7 Kleitman N. Sleep and Wakefulness. London (UK): University of Chicago Press; 1963.
8 Baker TL, Foutz AS, McNerney V, Mitler MM, Dement WC. Canine model of narcolepsy. Exp Neurol. 1982;75(3):729-42. https://doi.org/10.1016/0014-4886(82)90038-3
9 Matsuki K, Grumet FC, Lin X, Gelb M, Guilleminault C, Dement WC, Mignot E. DQ (rather than DR) gene marks susceptibility to narcolepsy. Lancet. 1992 Apr;339(8800):1052. https://doi.org/10.1016/0140-6736(92)90571-j
10 Nishino S, Ripley B, Overeem S, Lammers GJ, Mignot E. Hypocretin (orexin) transmission in human narcolepsy. Lancet. 2000 Jan;355(9197):39-40.
11 Nishino S, Kanbayashi T. Symptomatic narcolepsy, cataplexy and hypersomnia, and their implication in the hypothalamic hypocretin/orexin system. Sleep Med Rev. 2005 Aug;9(4):269-310. https://doi.org/10.1016/j.smrv.2005.03.004
12 Kok, SW, Overeem S, Visscher TLS, et al. Hypocretin deficiency in narcoleptic humans is associated with abdominal obesity. Obes Res. 2012;11(9):1147-54. https://doi.org/10.1038/oby.2003.156
13 Truzzi GM, Naufel MF, Tufik S, Coelho FM. Narcolepsy: the impact of aging, hypocretin deficiency, and years of formal education in olfactory function and abdominal obesity. Arq Neuropsiquiatr. 2021 Sep 6;79(9):808-15. https://doi.org/10.1590/0004-282X-ANP-2020-0352
14 Todman D. Narcolepsy: A historic review. Int J Neurology. 2007;9(2). https://ispub.com/IJN/9/2/7361