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CC BY-NC-ND 4.0 · Arq Neuropsiquiatr 2016; 74(09): 701-707
DOI: 10.1590/0004-282X20160105
ARTICLES

Sleep disorder investigation might be considered to be mandatory in attention deficit/hyperactivity disorder guideline

Investigação de distúrbio do sono deve ser considerada obrigatória e incluída no manejo de distúrbios do déficit de atenção/hiperatividade
Paulo Sérgio Azeredo Henriques Filho
1   Universidade de Brasília, Faculdade de Medicina, Programa de Graduação Ciências Médicas, Brasília DF, Brasil;
2   Universidade de Brasília, Faculdade de Medicina, Departamento de Patologia, Laboratório Interdisciplinar de Biociências e Laboratório de Pesquisa de Imunogenética e Doenças Crçnico-Degenerativas, Brasília DF, Brasil;
3   Hospital Regional de Taguatinga, Unidade de Clínica Médica, Departamento Clínico de Neurofiologia, Taguatinga DF, Brasil.
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ABSTRACT

Objective To determine the prevalence of obstructive sleep apnea (OSA) in children with attention deficit/hyperactive disorder (ADHD) and compare amplitude and latency of the P300 potential among children with and without OSA.

Method Sixty-one children with ADHD underwent oddball auditory attention tests for detection of P300 (ERPs) followed by an all-night polysomnography. The children were divided in two groups, those with and without OSA.

Results Significant decreased amplitude of the P300 potential was observed in children with OSA when compared with children without OSA.

Conclusion The study showed that sleep fragmentation as a result of OSA can exacerbate the attention disorder that characterizes ADHD, and highlights the importance of assessing the presence of OSA in the differential diagnosis of children with attention deficits.

RESUMO

Objetivo determinar a prevalência de apneia obstrutiva do sono (AOS) em crianças com déficit de atenção / hiperatividade (TDAH) e comparar amplitude e latência do potencial P300 entre as crianças com e sem AOS.

Método Sessenta e uma crianças com TDAH foram submetidos a testes de atenção auditiva com o paradigma oddball para a detecção de potenciais relacionados a eventos (PREs) do tipo P300, seguidos por polissonografia de noite inteira. As crianças foram divididas em dois grupos, crianças com e sem AOS.

Resultados Foi observada redução significativa da amplitude do potencial P300 em crianças com AOS quando comparadas com crianças sem AOS.

Conclusão O estudo mostrou que a fragmentação do sono, consequente a AOS, pode exacerbar o déficit de atenção, que caracteriza o TDAH, e destacou a importância de avaliar a presença de AOS no diagnóstico diferencial de crianças com déficit de atenção.

obstructive sleep apnea - event-related potential - P300 potential - attention deficit disorder with hyperactivity
apnéia do sono tipo obstrutiva - potencial evocado - potencial P300 - transtorno do déficit de atenção com hiperatividade


Publication History

Received: 04 September 2015

Accepted: 09 June 2016

Article published online:
06 September 2023

© 2023. Academia Brasileira de Neurologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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