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CC BY-NC-ND 4.0 · Arq Neuropsiquiatr 2016; 74(12): 974-981
DOI: 10.1590/0004-282X20160151
ARTICLE

The correlation between EDSS and cognitive impairment in MS patients. Assessment of a Brazilian population using a BICAMS version

Correlação entre EDSS e déficit cognitivo em pacientes com EM. Avaliação de uma população brasileira usando uma versão do BICAMS
Marco A. G. de Caneda
1   Hospital Moinhos de Vento, Instituto de Ensino e Pesquisa, Departamento de Neurologia, Grupo de Esclerose Múltipla, Porto Alegre RS, Brasil.
,
Maria Cecília A. de Vecino
1   Hospital Moinhos de Vento, Instituto de Ensino e Pesquisa, Departamento de Neurologia, Grupo de Esclerose Múltipla, Porto Alegre RS, Brasil.
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ABSTRACT

Multiple sclerosis (MS) may present with a cognitive impairment as disabling as the physical disabilities. Therefore, routine cognitive evaluation is pivotal. Valid and reliable neuropsychological tests are essential in follow-up and to define future therapeutic interventions.

Objectives

To investigate the correlation between the disabilities of MS patients and their cognitive impairment assessed by the Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS).

Methods

Forty patients with definitive diagnoses of MS were selected. The correlation coefficient (r) between the Expanded Disability Status Scale (EDSS) and the neuropsychological tests of BICAMS were calculated.

Results

The correlation was clinically substantial and significant with r = 0.55 (p < 0.01) in the Symbol Digit Modalities Test (SDMT), 0.54 (p < 0.01) in the Brief Visuospacial Memory Test (BVMT) and 0.40 (p < 0.05) in the California Verbal Learning Test (CVLT).

Conclusion

BICAMS has easy and satisfactory application and evaluation for routine visits and presents a significant correlation with the EDSS. Its use may be indicated for screening and monitoring of cognitive impairment in patients with MS.

RESUMO

A esclerose múltipla (EM) pode apresentar um déficit cognitivo (DC) tão devastador quanto suas debilidades físicas. Uma avaliação cognitiva rotineira é essencial e testes neuropsicológicos (TNs) validados e confiáveis são fundamentais no acompanhamento e definição de futuras intervenções terapêuticas.

Objetivos

Investigar a correlação entre o estado de incapacidade física de pacientes com EM e o comprometimento cognitivo, avaliado pelo Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS).

Métodos

Foram calculados coeficientes de correlação (r) entre a Expanded Disability Status Scale (EDSS) e resultados dos testes do BICAMS em quarenta pacientes com diagnóstico definitivo de EM.

Resultados

A correlação foi clinicamente substancial e significativa, com r = 0.55 (p < 0.01, no Symbol Digit Modalities Test (SDMT), 0.54 (p < 0.01) no Brief Visuospacial Memory Test (BVMT) e 0.40 (p < 0.05) no California Verbal Learning Test (CVLT).

Conclusão

O BICAMS é de fácil e satisfatória aplicação e avaliação em visitas de rotina e apresenta uma correlação significativa com a EDSS. Seu uso pode ser indicado como rotina no acompanhamento do (DC) em portadores de EM.

multiple sclerosis - cognition disorders - disabled persons
esclerose múltipla - transtornos cognitivos - pessoas com deficiência


Publikationsverlauf

Eingereicht: 10. Juli 2016

Angenommen: 01. September 2016

Artikel online veröffentlicht:
06. September 2023

© 2023. Academia Brasileira de Neurologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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