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CC BY-NC-ND 4.0 · Arq Neuropsiquiatr 2017; 75(06): 359-365
DOI: 10.1590/0004-282X20170050
ARTICLE

Potential role of a cognitive rehabilitation program following left temporal lobe epilepsy surgery

Reabilitação neuropsicológica em pacientes com epilepsia submetidos à lobectomia temporal dominante
Camila de Vasconcelos Geraldi
1   Universidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Neurociências e Ciências do Comportamento, Ribeirão Preto SP, Brasil;
2   UCL Institute of Neurology, Department of Clinical and Experimental Epilepsy, London, UK;
,
Sara Escorsi-Rosset
1   Universidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Neurociências e Ciências do Comportamento, Ribeirão Preto SP, Brasil;
,
Pamela Thompson
2   UCL Institute of Neurology, Department of Clinical and Experimental Epilepsy, London, UK;
3   Epilepsy Society Research Centre, Buckinghamshire, UK.
,
Ana C. Gargaro Silva
1   Universidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Neurociências e Ciências do Comportamento, Ribeirão Preto SP, Brasil;
,
Américo Ceiki Sakamoto
1   Universidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Neurociências e Ciências do Comportamento, Ribeirão Preto SP, Brasil;
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ABSTRACT

Research into memory and epilepsy has focused on measuring problems and exploring causes with limited attention directed at the role of neuropsychological rehabilitation in alleviating post-operative memory difficulties.

Objectives

To assess the effects of a memory rehabilitation program in patients with left temporal lobe epilepsy following surgery.

Methods

Twenty-four patients agreed to participate and 18 completed the study; nine received memory rehabilitation while nine had no input and were designated as controls. Verbal learning efficiency, naming abilities, memory subjective ratings, ecological activity measures and a language fMRI paradigm were used as outcome measures.

Results

Improved verbal learning and naming test performance, increase in memory strategy use and improved self-perception were observed following the rehabilitation. Changes in fMRI activation patterns were seen in the rehabilitation group over the long term.

Conclusion

The findings support the potential role of a cognitive rehabilitation program following left temporal lobe surgery.

RESUMO

As publicações na área de epilepsia e memória se focam em mensurar prejuízos e investigar causas, com poucos dados sobre reabilitação neuropsicológica em pacientes pós-cirúrgicos.

Objetivos

Avaliar os efeitos da reabilitação neuropsicológica em pacientes submetidos a lobectomia temporal dominante.

Métodos

Vinte e quatro pacientes iniciaram o estudo, apenas dezoito o concluíram, dos quais 9 foram participantes de sessões de reabilitação com enfoque em memória. Todos os participantes foram avaliados quanto a autopercepção de dificuldades de memória; ao uso de estratégias para minimizar tais dificuldades; a habilidade de nomeação e a aprendizagem verbal e foram submetidos à ressonância magnética funcional.

Resultados

Foi encontrado efeito significativo da reabilitação neuropsicológica na autopercepção de dificuldades de memória; no uso de estratégias compensatórias; na aprendizagem verbal e na nomeação. Alterações no padrão de ativação na RMf foram observadas no grupo submetido a reabilitação.

Conclusão

A reabilitação neuropsicológica pode beneficiar pacientes submetidos a lobectomia temporal antero-mesial dominante com prejuízos de memória.

epilepsy, temporal lobe - memory - neurologic rehabilitation - anterior temporal lobectomy
epilepsia do lobo temporal - memória - reabilitação neurológica - lobectomia temporal anterior


Publication History

Received: 15 September 2016

Accepted: 14 February 2017

Article published online:
05 September 2023

© 2023. Academia Brasileira de Neurologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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