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CC BY-NC-ND 4.0 · Arq Neuropsiquiatr 2017; 75(09): 609-613
DOI: 10.1590/0004-282X20170102
ARTICLES

Alpha band EEG coherence in healthy nonagenarians

Coerência da banda alfa do EEG em nonagenários saudáveis
Mario Silva Jorge
1   Universidade de São Paulo, São Paulo SP, Brasil;
,
Livia Spindola
1   Universidade de São Paulo, São Paulo SP, Brasil;
,
Joyce Haruyo Biancon Katata
2   UNEP Unidade Neuropsiquiátrica, São José dos Campos SP, Brasil.
,
Renato Anghinah
1   Universidade de São Paulo, São Paulo SP, Brasil;
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ABSTRACT

Electroencephalographic (EEG) coherence is a parameter that enables evaluation of cerebral connectivity. It may be related to the functional state of the brain. In the elderly, it may reflect the neuronal loss caused by aging.

Objective To describe characteristics of coherence in nonagenarians.

Methods We evaluated interhemispheric coherence for the alpha band in 42 cognitively normal individuals aged 90 to 101 years. Coherence values in the occipital electrode (O1O2), in the resting state with closed eyes, were calculated by means of spectral analysis using digital EEG EMSA 32 channels, 12 bits and a frequency of 200 Hz.

Results The mean coherence value for the alpha band at O1O2 was 0.65 (SD 0.13). No significant differences were found between men and women.

Conclusions The findings from this study did not show any decrease in interhemispheric coherence for the alpha band in cognitively normal nonagenarians. This may be useful as a standard value for this age group.

RESUMO

A coerência é um parâmetro que permite avaliar a conectividade cerebral, podendo se relacionar com o estado funcional do cérebro. Especialmente nos idosos, pode refletir a perda neuronal decorrente do envelhecimento.

Objetivo Descrever características da coerência em nonagenários.

Métodos Avaliamos a coerência interhemisferica para a banda alfa em 42 indivíduos cognitivamente normais entre 90 e 101 anos. Foram calculados através da análise espectral o valor da coerência nos eletrodos O1O2, em estado de repouso e olhos fechados, com EEG digital 32 canais marca EMSA 12 bits e frequência de amostragem 200 hz.

Resultados O valor médio da coerência para a banda alfa entre O1O2 foi de 0,65 (DP 0,13). Não encontramos diferenças significativas entre homens e mulheres.

Conclusão Os achados desse estudo não evidenciam diminuição da coerência interhemisferica para a banda alfa nos eletrodos O1O2 em nonagenários saudáveis e cognitivamente normais, podendo indicar um valor padrão para essa faixa etária.

electroencephalography - aged, 80 and over - health of the elderly - aging
eletroencefalografia - idoso de 80 anos ou mais - saúde do idoso - envelhecimento


Publication History

Received: 01 June 2017

Accepted: 20 June 2017

Article published online:
05 September 2023

© 2023. Academia Brasileira de Neurologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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  • References

  • 1 Silva FL. Computer-assisted EEG diagnosis: pattern recognition and brain mapping. In: Niedermeyer E, Silva FL, editors. Electrocephalography: basic principles, clinical applications, and related fields. 5th ed. Baltimore: Williams and Wilkins; 2005. p. 1233-63.
  • 2 Anghinah R. EEG spectral coherence. Rev Neurociências. 2005;13(1):50-3.
  • 3 Jorge MS, Botelho RV, Melo ACDP. Study of interhemispheric coherence on healthy adults. Arq Neuropsiquiatr. 2007;65(2B):377-80. https://doi.org/10.1590/S0004-282X2007000300002
  • 4 Gotman J. The use computers in analysis and display of EEG and evoked potential. In: Daly DD, Pedley TA, editors. Current practice of clinical electroencephalography. 2nd ed. Philadelphia: Lippincott Williams & Wilkins;1990. p. 51-83.
  • 5 Cibils D. Análise da coerência na doença de Alzheimer e no envelhecimento normal. In: Anghinah R, Luccas FJC. A neurofisiologia clinica no auxílio diagnóstico das demências. São Paulo: Biosintética; 1999. p. 63-8.
  • 6 Towle VL, Carder RK, Khorasani L, Lindberg D. Electrocorticographic coherence patterns. J Clin Neurophysiol. 1999;16(6):528-47. https://doi.org/10.1097/00004691-199911000-00005
  • 7 Gudmundsson S, Runarsson TP, Sigurdsson S, Eiriksdottir G, Johnsen K. Reliability of quantitative EEG features. Clin Neurophysiol. 2007;118(10):2162-71. https://doi.org/10.1016/j.clinph.2007.06.018
  • 8 Koyama K, Hirasawa H, Okubo Y, Karasawa A. Quantitative EEG correlates of normal aging in the elderly. Clin Electroencephalogr. 1997;28(3):160-5. https://doi.org/10.1177/155005949702800308
  • 9 Smith GE, Ivnik RJ, Malec JF, Kokmen E, Tangalos EG, Kurland LT. Mayo’s Older Americans Normative Studies (MOANS): factor structure of a core battery. Psychol Assess. 1992;4(3):382-90. https://doi.org/10.1037/1040-3590.4.3.382
  • 10 Folstein MF, Folstein SE, McHugh PR. “Mini-mental state”: a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12(3):189-98. https://doi.org/10.1016/0022-3956(75)90026-6
  • 11 Pfeffer RI, Kurosaki TT, Harrah CH, Chance JM, Filos S. Measurement of functional activities in older adults in the community. J Gerontol. 1982;37(3):323-9. https://doi.org/10.1093/geronj/37.3.323
  • 12 Katz S, Stroud MW. Functional assessment in geriatrics. J Am Geriatr Soc. 1989;37(3):267-72. https://doi.org/10.1111/j.1532-5415.1989.tb06820.
  • 13 Mattis S. Mental status examination for organic mental syndromes in the elderly patient. In: Bellak L, Karasu TB, eds Geriatric psychiatry: a handbook for psychiatrists and primary care physicians. New York: Grune & Stratton, 1976. p. 77-121.
  • 14 Klem GH, Lüders HO, Jasper HH, Elger C. The ten-twenty electrode system of the International Federation. Electroencephalogr Clin Neurophysiol Suppl. 1999;52(3):3-6.
  • 15 Luccas FJC, Braga NIO, Fonseca LC, Frochtengarten ML. Recomendações para o registro e interpretação do mapeamento topográfico do eletrencefalograma (EEG) e potenciais evocados sensoriais (PES). Parte I: aspectos gerais. Braz J Epilepsy Clin Neurophysiol. 1996;2:175-82.
  • 16 Rappelsberger P. The reference problem and mapping of coherence: a simulation study. Brain Topogr. 1989;2(1):63-72. https://doi.org/10.1007/BF01128844
  • 17 Locatelli T, Cursi M, Liberati D, Franceschi M, Comi G. EEG coherence in Alzheimer’s disease. Electroencephalogr Clin Neurophysiol. 1998;106(3):229-37. https://doi.org/10.1016/S0013-4694(97)00129-6
  • 18 Vysata O, Kukal J, Prochazka A, Pazdera L, Simko J, Valis M. Age-related changes in EEG coherence. Neurol Neurochir Pol. 2014;48(1):35-8. https://doi.org/10.1016/j.pjnns.2013.09.001
  • 19 Gonzalez Andino SL, Pascual Marqui RD, Valdes Sosa PA, Biscay Lirio R, Machado C, Diaz G et al. Brain electrical field measurements unaffected by linked earlobes reference. Electroencephalogr Clin Neurophysiol. 1990;75(3):155-60. https://doi.org/10.1016/0013-4694(90)90169-K
  • 20 Duffy FH, Mcanulty GB, Albert MS. Effects of age upon interhemispheric EEG coherence in normal adults. Neurobiol Aging. 1996;17(4):587-99. https://doi.org/10.1016/0197-4580(96)00007-3
  • 21 Kikuchi M, Wada Y, Koshino Y, Nanbu Y, Hashimoto T. Effect of normal aging upon interhemispheric EEG coherence: analysis during rest and photic stimulation Clin Electroencephalogr. 2000;31(4):170-4. https://doi.org/10.1177/155005940003100404
  • 22 Sloan EP, Fenton GW, Standage KP. Anticholinergic drug effects on quantitative electroencephalogram, visual evoked potential, and verbal memory. Biol Psychiatry. 1992;31(6):600-6. https://doi.org/10.1016/0006-3223(92)90246-V
  • 23 Koeda T, Knyazeva M, Njiokiktjien C, Jonkman EJ, De Sonneville L, Vildavsky V. The EEG in acallosal children. Coherence values in the resting state: left hemisphere compensatory mechanism? Electroencephalogr Clin NeurophysioI. 1995;95(6):397-407. https://doi.org/10.1016/0013-4694(95)00171-9
  • 24 Montplaisir J, Nielsen T, Cçté J, Boivin D, Rouleau I, Lapierre G. Interhemisphere EEG coherence before and after partial callosotomy. Clin Electroencephalogr. 1990;21(1):42-7. https://doi.org/10.1177/155005949002100114
  • 25 Weis S, Kimbacher M, Wenger E, Neuhold A. Morphometric analysis of the corpus callosum using MR: correlation of measurements with aging in healthy individuals. AJNR Am J Neuroradiol. 1993;14(3):637-45.
  • 26 Hogan M, Collins P, Keane M, Kilmartin L, Kaiser J, Kenney J et al. Electroencephalographic coherence, aging, and memory: distinct responses to background context and stimulus repetition in younger, older, and older declined groups. Exp Brain Res. 2011;212(2):241-55. https://doi.org/10.1007/s00221-011-2726-8
  • 27 Anghinah R, Kanda PA, Jorge MS, Lima EE, Pascuzzi L, Melo AC. [Alpha band coherence analysis of EEG in healthy adult and Alzheimer’s type dementia subjects]. Arq Neuropsiquiatr. 2000;58(2A):272-5. Portuguese. https://doi.org/10.1590/S0004-282X220170102200011