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CC BY-NC-ND 4.0 · Arq Neuropsiquiatr 2017; 75(10): 751-753
DOI: 10.1590/0004-282X20170116
Historical Note

Lafora and Trétiakoff: the naming of the inclusion bodies discovered by Lewy

Lafora e Trétiakoff: a denominação dos corpos de inclusão descobertos por Lewy
Eliasz Engelhardt
Universidade Federal do Rio de Janeiro, Unidade de Neurologia Cognitiva e do Comportamento, Instituto de Neurologia/Centro para Doença de Alzheimer -Instituto de Psiquiatria, Rio de Janeiro RJ, Brasil
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ABSTRACT

Fritz Heinrich Jakob Lewy described, for the first time, in 1912, novel peculiar inclusions in neurons of certain brain nuclei in patients with Paralysis agitans, and compared his finding to the amyloid bodies described by Lafora one year before. Gonzalo Rodriguez Lafora studied one patient with Paralysis agitans, in 1913, and recognized, described, and depicted structures identical to those previously reported by Lewy. He was the first to acknowledge Lewy's finding, and also the first to name such inclusions after the discoverer – cuerpos intracelulares de Lewy (Lewy bodies). Konstantin Nikolaevich Trétiakoff named the inclusions he found in neurons of the substantia nigra of patients with Parkinson's disease as corps de Lewy (Lewy bodies), in 1919. Trétiakoff has unanimously received the credit for the eponym. However, Lafora's earlier description should make him deserving of the authorship of the eponym.

RESUMO

Fritz Heinrich Jakob Lewy descreveu pela primeira vez, em 1912, inclusões singulares inéditas em neurçnios de certos núcleos do cérebro em casos de Paralysis agitans e comparou seu achado aos corpos amilóides, como descrito por Lafora um ano antes. Gonzalo Rodriguez Lafora estudou um caso de Paralysis agitans, em 1913,e reconheceu, descreveu e representou estruturas idênticas às recentemente relatadas por Lewy. Foi o primeiro a reconhecer o achado de Lewy e também o primeiro a denominar tais inclusões segundo seu descobridor – cuerpos intracelulares de Lewy (corpos de Lewy). Konstantin Nikolaevich Tretiakoff designou as inclusões que encontrou em neurçnios da substantia nigra em casos de doença de Parkinson de corps de Lewy (corpos de Lewy), em 1919. Ele recebeu o crédito pelo epçnimo de modo unânime. Entretanto, a descrição anterior de Lafora deveria fazê-lo merecedor da autoria do epçnimo.

Keywords:

Fritz Heinrich Jakob Lewy - Gonzalo Rodriguez Lafora - Konstantin Nikolaevich Tretiakoff - inclusion bodies - Lewy bodies - Paralysis agitans - Parkinson disease

Palavras-chave:

Fritz Heinrich Jakob Lewy - Gonzalo Rodriguez Lafora - Konstantin Nikolaevich Tretiakoff - corpos de inclusão - corpos de Lewy - Paralysis agitans - doença de Parkinson


Publication History

Received: 25 April 2017

Accepted: 04 July 2017

Article published online:
04 September 2023

© 2023. Academia Brasileira de Neurologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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