PDF herunterladen
CC BY-NC-ND 4.0 · Arq Neuropsiquiatr 2018; 76(04): 225-230
DOI: 10.1590/0004-282X20180026
Article

Association between cognitive function and parameters of echocardiography and coronary artery angiography

Associação entre a função cognitiva e parâmetros de ecocardiografia e angiografia da artéria coronária
Mohammad Hashemi
1   Isfahan University of Medical Sciences, Interventional Research Center, Cardiovascular Department, Isfahan, Iran
,
Zahra Teimouri Jervekani
2   Isfahan University of Medical Sciences, Heart Failure Research Center, Cardiovascular Department, Isfahan, Iran
,
Shahrzad Mortazavi
3   Isfahan University of Medical Sciences, Psychiatry Department, Isfahan, Iran
,
Mohammad Reza Maracy
4   Isfahan University of Medical Sciences, Department of Epidemiology and Biostatics, Isfahan, Iran
,
Majid Barekatain
5   Isfahan University of Medical Sciences, Psychosomatic Research Center, Psychiatry Department, Isfahan, Iran
› Institutsangaben
› Weitere Informationen
Auch verfügbar auf
   Lizenzen und Reprints

ABSTRACT

We aimed to determine whether there is an association between cognition and the results of echocardiography and angiography, based on neuropsychological assessments.

Methods: We assessed the cognition of 85 patients who had recently undergone coronary artery angiography. We calculated the Gensini score for the coronary artery disease index. We also performed echocardiography to find indices of cardiac functioning.

Results: The lower left ventricular ejection fraction correlated with lower scores on visuospatial, executive function, processing speed/attention and verbal memory capacities (p ≤ 0.05). A higher Gensini score and left atrial size correlated with lower executive function and processing speed/attention (p ≤ 0.05). In the group of patients with an impaired cognitive state, higher Gensini scores correlated with decreased processing speed/attention (p = 0.01) and the e' index was associated with lower capacity of executive function (p = 0.05).

Conclusion: Decreased processing speed/attention and executive function may correlate with cardiac dysfunction and coronary artery disease. The Color Trail Test may be considered for simple screening for cognitive problems in elderly patients with coronary artery disease or diastolic dysfunction.

RESUMO

O objetivo deste estudo é encontrar associação entre cognição e resultados de exames ecocardiográficos e angiográficos, com base em avaliações neuropsicológicas.

Método: Foi avaliada a cognição de 85 pacientes que foram submetidos a angiografia coronária. O escore de Gensini foi calculado para o índice de doença arterial coronariana (DAC). Foi realizado também, o exame ecocardiográfico a fim de descobrir os índices de funcionamento cardíaco.

Resultados: A fração de ejeção do ventrículo inferior esquerdo está correlacionada com a baixa pontuação na capacidade visual e espacial, função executiva, velocidade de processamento/atenção e memória verbal (p ≤ 0,05). Alto escore de Gensini e tamanho do átrio esquerdo correlacionados com baixa função executiva, velocidade de processamento/atenção (p ≤ 0,05). No grupo de pacientes com estado cognitivo prejudicado, alto escore de Gensini correlacionado com diminuição da velocidade de processamento/atenção (p = 0,01) e índice e' associado a baixa capacidade da função executiva (p = 0,05).

Conclusão: Diminuição da velocidade de processamento/atenção e da função executiva pode estar correlacionado a disfunção cardíaca e DAC. O Color Trail Test pode ser considerado para uma triagem simples de problemas cognitivos em pacientes idosos com DAC ou disfunção diastólica.

Keywords:

cognition - coronary artery disease - echocardiography - left ventricular function

Palavras-chave:

cognição - doença da artéria coronariana - ecocardiografia - função ventricular esquerda


Publikationsverlauf

Eingereicht: 21. Oktober 2017

Angenommen: 22. Januar 2018

Artikel online veröffentlicht:
28. August 2023

© 2023. Academia Brasileira de Neurologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

Thieme Revinter Publicações Ltda.
Rua do Matoso 170, Rio de Janeiro, RJ, CEP 20270-135, Brazil

 

  • References

  • 1 Lutz W, Sanderson W, Scherbov S. The coming acceleration of global population ageing. Nature. 2008 Feb;451(7179):716-9. https://doi.org/10.1038/nature06516
  • 2 Vos SJ, Xiong C, Visser PJ, Jasielec MS, Hassenstab J, Grant EA et al. Preclinical Alzheimer's disease and its outcome: a longitudinal cohort study. Lancet Neurol. 2013 Oct;12(10):957-65. https://doi.org/10.1016/S1474-4422(13)70194-7
  • 3 Patterson C, Feightner JW, Garcia A, Hsiung GY, MacKnight C, Sadovnick AD. Diagnosis and treatment of dementia: 1. Risk assessment and primary prevention of Alzheimer disease. CMAJ. 2008 Feb;178(5):548-56. https://doi.org/10.1503/cmaj.070796
  • 4 Paciaroni M, Bogousslavsky J. Connecting cardiovascular disease and dementia: further evidence. J Am Heart Assoc. 2013 Dec;2(6):e000656. https://doi.org/10.1161/JAHA.113.000656
  • 5 Fillit H, Nash DT, Rundek T, Zuckerman A. Cardiovascular risk factors and dementia. Am J Geriatr Pharmacother. 2008 Jun;6(2):100-18. https://doi.org/10.1016/j.amjopharm.2008.06.004
  • 6 Siuda J, Gorzkowska A, Opala G, Ochudło S. Vascular risk factors and intensity of cognitive dysfunction in MCI. J Neurol Sci. 2007 Jun;257(1-2):202-5. https://doi.org/10.1016/j.jns.2007.01.034
  • 7 Leto L, Feola M. Cognitive impairment in heart failure patients. J Geriatr Cardiol. 2014 Dec;11(4):316-28. https://doi.org/10.11909/j.issn.1671-5411.2014.04.007
  • 8 Barekatain M, Askarpour H, Zahedian F, Walterfang M, Velakoulis D, Maracy MR et al. The relationship between regional brain volumes and the extent of coronary artery disease in mild cognitive impairment. J Res Med Sci. 2014 Aug;19(8):739-45.
  • 9 Arangalage D, Ederhy S, Dufour L, Joffre J, Van der Vynckt C, Lang S et al. Relationship between cognitive impairment and echocardiographic parameters: a review. J Am Soc Echocardiogr. 2015 Mar;28(3):264-74. https://doi.org/10.1016/j.echo.2014.11.009
  • 10 Kovacic JC, Castellano JM, Fuster V. The links between complex coronary disease, cerebrovascular disease, and degenerative brain disease. Ann N Y Acad Sci. 2012 Apr;1254(1):99-105. https://doi.org/10.1111/j.1749-6632.2012.06482.x
  • 11 van den Hurk K, Reijmer YD, van den Berg E, Alssema M, Nijpels G, Kostense PJ et al. Heart failure and cognitive function in the general population: the Hoorn Study. Eur J Heart Fail. 2011 Dec;13(12):1362-9. https://doi.org/10.1093/eurjhf/hfr138
  • 12 Barekatain M, Alavirad M, Tavakoli M, Emsaki G, Maracy MR. Cognitive rehabilitation in patients with nonamnestic mild cognitive impairment. J Res Med Sci. 2016 Nov;21(1):101. https://doi.org/10.4103/1735-1995.193173
  • 13 Jafari Z, Steffen Moritz P, Zandi T, Aliakbari Kamrani A, Malyeri S. Psychometric properties of Persian version of the Rey Auditory-Verbal Learning Test (RAVLT) among the elderly. Iran J Psychiatry. 2010;16(1):56-64.
  • 14 Nilipour R. Persian aphasia naming test. Tehran: University of Social Welfare and Rehabilitation Sciences; 2012.
  • 15 Nilipour R, Pourshahbaz A, Ghoreyshi ZS. Reliability and validity of bedside version of Persian WAB (P-WAB-1). Basic Clin Neurosci. 2014 Oct;5(4):253-8.
  • 16 Mann DL, Zipes DP, Libby P, Bonow RO. Braunwald's heart disease: a textbook of cardiovascular medicine. Philadelphia: Elsevier Health Sciences; 2014.
  • 17 Gensini GG. A more meaningful scoring system for determining the severity of coronary heart disease. Am J Cardiol. 1983 Feb;51(3):606. https://doi.org/10.1016/S0002-9149(83)80105-2
  • 18 Harkness K, Demers C, Heckman GA, McKelvie RS. Screening for cognitive deficits using the Montreal cognitive assessment tool in outpatients ≥65 years of age with heart failure. Am J Cardiol. 2011 Apr;107(8):1203-7. https://doi.org/10.1016/j.amjcard.2010.12.021
  • 19 Vogels RL, Scheltens P, Schroeder-Tanka JM, Weinstein HC. Cognitive impairment in heart failure: a systematic review of the literature. Eur J Heart Fail. 2007 May;9(5):440-9. https://doi.org/10.1016/j.ejheart.2006.11.001
  • 20 Athilingam P, D'Aoust RF, Miller L, Chen L. Cognitive profile in persons with systolic and diastolic heart failure. Congest Heart Fail. 2013 Jan-Feb;19(1):44-50. https://doi.org/10.1111/chf.12001
  • 21 Park CM, Williams ED, Chaturvedi N, Tillin T, Stewart RJ, Richards M et al. Associations between left ventricular dysfunction and brain structure and function: findings from the SABRE (Southall and Brent revisited) study. J Am Heart Assoc. 2017 Apr;6(4):e004898. https://doi.org/10.1161/JAHA.116.004898
  • 22 Cupples SA, Stilley CS. Cognitive function in adult cardiothoracic transplant candidates and recipients. J Cardiovasc Nurs. 2005 Sep-Oct;20(5 Suppl):S74-87. https://doi.org/10.1097/00005082-200509001-00009
  • 23 Hoth KF, Poppas A, Ellison KE, Paul RH, Sokobin A, Cho Y et al. Link between change in cognition and left ventricular function following cardiac resynchronization therapy. J Cardiopulm Rehabil Prev. 2010 Nov-Dec;30(6):401-8. https://doi.org/10.1097/HCR.0b013e3181e1739a
  • 24 Caldas JR, Panerai RB, Haunton VJ, Almeida JP, Ferreira GS, Camara L et al. Cerebral blood flow autoregulation in ischemic heart failure. Am J Physiol Regul Integr Comp Physiol. 2017 Jan;312(1):R108-13. https://doi.org/10.1152/ajpregu.00361.2016
  • 25 Haring B, Leng X, Robinson J, Johnson KC, Jackson RD, Beyth R et al. Cardiovascular disease and cognitive decline in postmenopausal women: results from the Women's Health Initiative Memory Study. J Am Heart Assoc. 2013 Dec;2(6):e000369. https://doi.org/10.1161/JAHA.113.000369
  • 26 Vidal JS, Sigurdsson S, Jonsdottir MK, Eiriksdottir G, Thorgeirsson G, Kjartansson O et al. Coronary artery calcium, brain function and structure: the AGES-Reykjavik Study. Stroke. 2010 May;41(5):891-7. https://doi.org/10.1161/STROKEAHA.110.579581
  • 27 Karadag B, Ozyigit T, Ozben B, Kayaoglu S, Altuntas Y. Relationship between left atrial volume index and cognitive decline in elderly patients with sinus rhythm. J Clin Neurosci. 2013 Aug;20(8):1074-8. https://doi.org/10.1016/j.jocn.2012.10.021
  • 28 Etgen T, Sander D, Bickel H, Förstl H. Mild cognitive impairment and dementia: the importance of modifiable risk factors. Dtsch Arztebl Int. 2011 Nov;108(44):743-50. https://doi.org/10.3238/arztebl.2011.0743
  • 29 Hawkins LA, Kilian S, Firek A, Kashner TM, Firek CJ, Silvet H. Cognitive impairment and medication adherence in outpatients with heart failure. Heart Lung. 2012 Nov-Dec;41(6):572-82. https://doi.org/10.1016/j.hrtlng.2012.06.001
  • 30 Almeida OP, Beer C, Lautenschlager NT, Arnolda L, Alfonso H, Flicker L. Two-year course of cognitive function and mood in adults with congestive heart failure and coronary artery disease: the Heart-Mind Study. Int Psychogeriatr. 2012 Jan;24(1):38-47. https://doi.org/10.1017/S1041610211001657