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CC BY-NC-ND 4.0 · Arq Neuropsiquiatr 2018; 76(04): 273-276
DOI: 10.1590/0004-282X20180021
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Pain in Charcot-Marie-Tooth disease: an update

Dor na doença de Charcot-Marie-Tooth: atualização
Helen Azevedo
1   Universidade Federal Fluminense, Departamento de Neurologia / Neurociências, Setor de doenças Neuromusculares, Niterói RJ, Brasil
,
Camila Pupe
1   Universidade Federal Fluminense, Departamento de Neurologia / Neurociências, Setor de doenças Neuromusculares, Niterói RJ, Brasil
,
Rouse Pereira
1   Universidade Federal Fluminense, Departamento de Neurologia / Neurociências, Setor de doenças Neuromusculares, Niterói RJ, Brasil
,
Osvaldo J. M. Nascimento
1   Universidade Federal Fluminense, Departamento de Neurologia / Neurociências, Setor de doenças Neuromusculares, Niterói RJ, Brasil
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ABSTRACT

Charcot-Marie-Tooth (CMT) disease, the most common inherited peripheral neuropathy, has pain as one of its clinical features, yet it remains underdiagnosed and undertreated. This literature review assessed data related to pain from CMT to determine its prevalence, type and importance as a symptom, which, unlike other symptoms, is likely to be treated. The research encompassed 2007 to 2017 and included five articles that addressed pain from CMT. All of the papers concurred that pain is frequently present in CMT patients, yet its classification remains undefined as there has been no consensus in the literature about the mechanisms that cause it.

RESUMO

A doença de Charcot-Marie-Tooth (CMT), a neuropatia periférica hereditária mais comum, tem a dor como uma de suas características clínicas, a qual permanece subdiagnosticada e subtratada. Essa revisão de literatura avaliou os dados relacionados à dor em CMT com objetivo de observar sua prevalência, tipo e importância como sintoma que, em detrimento de outros, é possível ser tratado. O intervalo da pesquisa foi entre 2007 e 2017, através de cinco artigos abordando a dor em CMT. Todos os artigos concordam que a dor é frequente nos pacientes com a doença de CMT e a sua classificação permanece indefinida por não haver consenso na literatura sobre os mecanismos da dor.

Keywords:

Charcot-Marie-Tooth disease - pain

Palavras-chave:

doença de Charcot-Marie-Tooth - dor


Publication History

Received: 24 September 2017

Accepted: 22 January 2018

Article published online:
28 August 2023

© 2023. Academia Brasileira de Neurologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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