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J Pediatr Infect Dis 2014; 09(02): 119-121
DOI: 10.3233/JPI-140422
Case Report
Georg Thieme Verlag KG Stuttgart – New York

Plasmablastic lymphoma with an extra-oral location in a child with human immunodeficiency virus infection

Satarupa Mukherjee Panja
a   Department of pediatrics, Medical College and Hospital, Kolkata, India
,
Buddhadev Panja
b   Department of pharmacology, MGM Medical College and LSK Hospital, Bihar, India
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Publication History

24 March 2014

15 June 2014

Publication Date:
28 July 2015 (online)

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Abstract

Plasmablastic lymphoma (PBL) is a rare type of non-Hodgkin lymphoma frequently related to HIV infection. We report a case of PBL in a 7 year old female child with transfusion-acquired HIV infection on antiretroviral therapy (ART). The presentation was a swelling in the skull and cervical lymphadenopathy. CT scan revealed bony erosions with meningeal enhancement. The patient was started on chemotherapy and cranial irradiation but succumbed to death in 5 months. This is the first reported case of PBL involving the skull and meninges in a HIV-infected child.

Keywords

HIV - Plasmablastic lymphoma - skull