Severe complicated mastoiditis caused by nontypable Haemophilus influenzae

Ellen Bamberger; Isaac Srugo; Elena Segal; Oded Glazer; Rabia Shihada; Alexander Brodsky; Jacob Braun; Michal Luntz

doi:10.3233/JPI-2011-0283

Journal of Pediatric Infectious Diseases, Inhaltsverzeichnis

J Pediatr Infect Dis 2011; 06(01): 041-044
DOI: 10.3233/JPI-2011-0283

Georg Thieme Verlag KG Stuttgart – New York

Severe complicated mastoiditis caused by nontypable Haemophilus influenzae

Autor*innen

Ellen Bamberger

^aDepartment of Clinical Microbiology, Bnai Zion Medical Center, Technion – Israel Institute of Technology, Haifa, Israel

^bDepartment of Pediatrics, Bnai Zion Medical Center, Technion – Israel Institute of Technology, Haifa, Israel
Isaac Srugo

^aDepartment of Clinical Microbiology, Bnai Zion Medical Center, Technion – Israel Institute of Technology, Haifa, Israel

^bDepartment of Pediatrics, Bnai Zion Medical Center, Technion – Israel Institute of Technology, Haifa, Israel
Elena Segal

^cRuth and Bruce Rappaport Faculty of Medicine, Technion – Israel Institute of Technology, Haifa, Israel
Oded Glazer

^bDepartment of Pediatrics, Bnai Zion Medical Center, Technion – Israel Institute of Technology, Haifa, Israel
Rabia Shihada

^dDepartment of Otolaryngology-Head and Neck Surgery, Bnai Zion Medical Center, Technion, Israel – Institute of Technology, Haifa, Israel
Alexander Brodsky

^dDepartment of Otolaryngology-Head and Neck Surgery, Bnai Zion Medical Center, Technion, Israel – Institute of Technology, Haifa, Israel
Jacob Braun

^eDepartment of Radiology, Bnai Zion Medical Center, Technion – Israel Institute of Technology, Haifa, Israel
Michal Luntz

^dDepartment of Otolaryngology-Head and Neck Surgery, Bnai Zion Medical Center, Technion, Israel – Institute of Technology, Haifa, Israel

Verantwortlicher Herausgeber dieser Rubrik:

Abstract

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Abstract

Non-typable Haemophilus influenzae (NTHi) is emerging as an important cause of invasive disease in immunized children. We describe a healthy, fully immunized 4-year old child who presented with bacteremia due to NTHi without overt acute otitis media (AOM), and subsequently developed severe mastoiditis complicated by sigmoid sinus thrombosis. Although, mastoiditis is typically regarded as a complication of AOM, those cases without antecedent AOM may represent an entirely different pathophysiological process with NTHi bacteremia seeding the mastoid. We present another example of the potential invasiveness of NTHi with a temporal sequence of events whereby NTHi bacteremia seeds the mastoid. This may represent novel sequelae of NTHi infection.

Keywords

Non-typable Haemophilus influenzae - mastoiditis - bacteremia

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