A HIV-infected adolescent with polycystic ovary syndrome

Prapai Dejkhamron; Kevalee Unachak; Manik Chhabra; Peninnah Oberdorfer

doi:10.3233/JPI-2011-0284

Journal of Pediatric Infectious Diseases, Table of Contents

J Pediatr Infect Dis 2011; 06(01): 045-049
DOI: 10.3233/JPI-2011-0284

Georg Thieme Verlag KG Stuttgart – New York

A HIV-infected adolescent with polycystic ovary syndrome

Authors

Prapai Dejkhamron

^aDepartment of Pediatrics, Division of Endocrinology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
Kevalee Unachak

^aDepartment of Pediatrics, Division of Endocrinology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
Manik Chhabra

^bDepartment of Medicine, University of Minnesota, Minneapolis, MN, USA
Peninnah Oberdorfer

^cDepartment of Pediatrics, Division of Infectious Diseases, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand

Subject Editor:

Abstract

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Abstract

We report a case of polycystic ovary syndrome in a 15-year-old human immunodeficiency virus-infected female on highly active antiretroviral therapy who developed hypertriglyceridemia, hyperinsulinemia due to insulin resistance, and hyperandrogenism. Ultrasonography showed multiple small follicles at the right ovary and lobulated follicles at the left ovary. Treatment of polycystic ovary syndrome included insulin sensitizing agents (metformin, pioglitazone) and a contraceptive for hyperandrogenism. We also encouraged life style modification including regular exercise and dietary fat restriction. She attained menarche 1 month after initiation of treatment.

Keywords

PCOS - HIV - HAART

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