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J Pediatr Infect Dis 2011; 06(04): 265-267
DOI: 10.3233/JPI-2012-0333
Georg Thieme Verlag KG Stuttgart – New York

Kawasaki disease in the neonatal period[1]

Sarah Mitchell
a   Neonatal Paediatrics, Child and Adolescent Health Service, Perth, Australia
,
Joshua Francis
b   Department of Paediatrics and Adolescent Medicine, Princess Margaret Hospital for Children, Perth, Australia
,
David Burgner
c   School of Paediatrics and Child Health, University of Western Australia, Perth, Australia
d   Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Australia
› Author Affiliations
Subject Editor:
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Publication History

22 March 2012

22 March 2012

Publication Date:
28 July 2015 (online)

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Abstract

Kawasaki disease (KD) is rare in neonates, who have fewer cardinal diagnostic features, potentially contributing to delayed diagnosis and worse outcome. We describe two infants who developed features consistent with incomplete KD in the first three weeks of life, who are amongst the youngest ever reported. The suggestive clinical features and lack of alternative aetiology prompted treatment of KD, with excellent response and no coronary artery sequelae. Current diagnostic guidelines are recognized to be relatively insensitive in infants. KD should be considered in infants with prolonged fever, irrespective of other clinical features.

Keywords

Kawasaki disease - neonate - infant - diagnosis

1 In memory of Sarah Mitchell (1966–2008), friend and colleague.