The use of MRS in the evaluation of pediatric epilepsy

Paul A. Caruso; Jason Johnson; Ron Thibert; Otto Rapalino; Sandra Rincon; Eva-Maria Ratai

doi:10.3233/PEP-13046

Journal of Pediatric Epilepsy, Inhaltsverzeichnis

Journal of Pediatric Epilepsy 2013; 02(01): 033-048
DOI: 10.3233/PEP-13046

Review Article

Georg Thieme Verlag KG Stuttgart – New York

The use of MRS in the evaluation of pediatric epilepsy

Paul A. Caruso

^aDivision of Neuroradiology, Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA

,

Jason Johnson

^aDivision of Neuroradiology, Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA

,

Ron Thibert

^bEpilepsy Service, Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA

,

Otto Rapalino

^aDivision of Neuroradiology, Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA

,

Sandra Rincon

^aDivision of Neuroradiology, Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA

,

Eva-Maria Ratai

^aDivision of Neuroradiology, Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA

^cAthinoula A. Martinos Center for Biomedical Imaging, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA

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Abstract

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Abstract

This chapter is a practical “why, how to, and when” chapter, written in three parts to address three questions that arise when the epileptologist or neuroimager evaluates a patient with epilepsy. Why do magnetic resonance spectroscopy (MRS)? How to do MRS in the patient with epilepsy? When, that is, in what clinical-imaging setting, can MRS help to diagnose or manage the patient with epilepsy?

Keywords

MRI - MRS - epilepsy - inborn error of metabolism - malformation of cortical development - focal cortical dysplasia - tumor - neoplasm

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