PDF herunterladen
Journal of Pediatric Epilepsy 2012; 01(01): 065-067
DOI: 10.3233/PEP-2012-010
Georg Thieme Verlag KG Stuttgart – New York

Hypouricemia in association with carbamazepine overdose

Mas Ahmed
a   Department of Pediatrics, Queen's University Hospital, London, UK
,
Tiffany McCarthy
a   Department of Pediatrics, Queen's University Hospital, London, UK
› Institutsangaben
Verantwortlicher Herausgeber dieser Rubrik:
Weitere Informationen

Publikationsverlauf

17. Mai 2010

16. September 2010

Publikationsdatum:
27. Juli 2015 (online)

Auch verfügbar auf
  als PDF herunterladen  Lizenzen und Reprints

Abstract

An 11-year-old Caucasian boy on carbamazepine (CBZ) because of his idiopathic epilepsy presented with psychosis and cyclic coma. Further evaluation revealed CBZ overdose in association with isolated hypouricemia. In this case, persistent low serum uric acid was found in the absence of other causes of hypouricemia, and the serum uric acid remained below normal until after return of blood CBZ level to the therapeutic blood range. CBZ overdose should be considered in patients with low level of uric acid in blood and psychosis or confusion.

Keywords

Overdose - hypouricemia - hypouricuria - purine - carbamazepine