Non-infectious pulmonary complications of hematopoietic stem cell transplantation

Courtney Rowan; Orkun Baloglu; Jennifer McArthur

doi:10.3233/PIC-14095

Journal of Pediatric Intensive Care, Table of Contents

J Pediatr Intensive Care 2014; 03(03): 133-146
DOI: 10.3233/PIC-14095

Review Article

Georg Thieme Verlag KG Stuttgart – New York

Non-infectious pulmonary complications of hematopoietic stem cell transplantation

Authors

Courtney Rowan

^aDepartment of Pediatrics, Section of Critical Care, Indiana University School of Medicine, Indianapolis, IN, USA
Orkun Baloglu

^bDepartment of Pediatrics, Division of Critical Care Medicine, Medical College of Wisconsin, Milwaukee, WI, USA
Jennifer McArthur

^bDepartment of Pediatrics, Division of Critical Care Medicine, Medical College of Wisconsin, Milwaukee, WI, USA

Subject Editor:

Abstract

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Abstract

Noninfectious pulmonary complications of hematopoietic stem cell transplant are currently more prevalent than infectious complications. Unfortunately, the pathophysiology basis is not completely understood. However, there is a string association with graft-versus-host disease for many of them. Therefore, an important component of their pathophysiology is likely an allo-immune response. There is much research that needs to be conducted to improve the less than optimal outcomes for these disorders.

Keywords

Hematopoietic cell transplant - pulmonary complications - graft versus host disease

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