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J Pediatr Intensive Care 2014; 03(03): 091-101
DOI: 10.3233/PIC-14101
Review Article
Georg Thieme Verlag KG Stuttgart – New York

Pediatric hematopoietic cell transplantation

Kathryn Walsh
a   Department of Anesthesia and Critical Care, Boston Children's Hospital, Boston, MA, USA
,
Steven Margossian
b   Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA
,
Christine N. Duncan
b   Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA
› Author Affiliations
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Further Information

Publication History

12 July 2014

04 November 2014

Publication Date:
28 July 2015 (online)

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Abstract

Hematopoietic cell transplantation is a potentially curative therapeutic modality for a wide range of pediatric malignant and nonmalignant diseases. Hematopoietic cell transplantation has evolved over time to include more indications for transplantation and broad-spectrum treatment and supportive care strategies. This review will address the process of transplantation, donor and stem cell sources, complications, and transplantable diseases.

Keywords

Hematopoietic cell transplantation - stem cell transplantation - hematopoietic stem cell transplantation - bone marrow transplant - children - pediatrics