Download PDF
Nuklearmedizin 2009; 48(02): 71-78
DOI: 10.3413/nukmed-0220
Positionspapier Nuklearkardiologie
Schattauer GmbH

Position paper nuclear cardiology: Update 2008

State-of-the-art of scintigraphic methodsPositionspapier Nuklear kardiologie: Update 2008Aktueller Stand der szintigraphischen Methodik
M. Schäfers   *
1   Klinik und Poliklinik für Nuklearmedizin, Universitätsklinikum Münster
,
F. Bengel   *
2   Cardiovascular Nuclear Medicine, Johns Hopkins University Medical Institutions, Baltimore, USA
,
U. Büll   *
3   Klinik und Poliklinik für Nuklearmedizin, UK Aachen
,
W. Burchert   *
4   Institut für Radiologie, Nuklearmedizin und Molekulare Bildgebung, Herz- und Diabeteszentrum NRW, Universitätsklinik der Ruhr-Universität Bochum, Bad Oeynhausen
,
P. Kies   *
1   Klinik und Poliklinik für Nuklearmedizin, Universitätsklinikum Münster
,
R. Kluge   *
5   Klinik und Poliklinik für Nuklearmedizin, UK Leipzig
,
B. J. Krause   *
7   Nuklearmedizinische Klinik und Poliklinik, TU München
,
O. Lindner   *
4   Institut für Radiologie, Nuklearmedizin und Molekulare Bildgebung, Herz- und Diabeteszentrum NRW, Universitätsklinik der Ruhr-Universität Bochum, Bad Oeynhausen
,
C. Nienaber   *
6   Klinik und Poliklinik für Innere Medizin – Kardiologie, Klinikum der Universität Rostock
,
B. Nowak   *
3   Klinik und Poliklinik für Nuklearmedizin, UK Aachen
,
W. Schäfer   *
3   Klinik und Poliklinik für Nuklearmedizin, UK Aachen
,
O. Schober   *
1   Klinik und Poliklinik für Nuklearmedizin, Universitätsklinikum Münster
,
M. Schwaiger   *
7   Nuklearmedizinische Klinik und Poliklinik, TU München
,
S. Silber   *
8   Kardiologische Gemeinschaftspraxis und Praxisklinik in der Klinik Dr. Müller, München
,
L. Stegger   *
1   Klinik und Poliklinik für Nuklearmedizin, Universitätsklinikum Münster
,
J. vom Dahl   *
9   Kliniken Maria Hilf GmbH, Klinik für Kardiologie, Mönchengladbach
,
R. Zimmermann   *
10   Medizinische Klinik I – Kardiologie, Klinikum Pforzheim
› Author Affiliations
Further Information

Publication History

Eingegangen: 17 October 2008

angenommen: 17 January 2008

Publication Date:
22 January 2018 (online)

Also available at
    Permissions and Reprints

Summary

Nuclear cardiology is well established in clinical diagnostic algorithms for many years. This is an update 2008 of the first common position paper of the German Association of Nuclear Medicine and the German Association of Cardiology, Heart and Circulation Research published in 2001 aiming at an overview of state-of-the-art scintigraphic methods.

Zusammenfassung

Die nuklearkardiologischen Verfahren besitzen seit langem einen festen klinischen Stellenwert. Das “Update 2008” des 2001 erstmals verfassten Positionspapieres der Deutschen Gesellschaft für Nuklearmedizin und der Deutschen Gesellschaft für Kardiologie, Herz- und Kreislaufforschung bietet einen aktuellen Überblick Über die szintigraphische Methodik.

Keywords

Position paper - nuclear cardiology - myocardial scintigraphy - SPECT - PET

Schlüsselwörter

Positionspapier - Nuklearkardiologie - Myokardszintigraphie - SPECT - PET

* im Namen der Arbeitsgemeinschaft “Kardiovaskuläre Nuklearmedizin” der Deutschen Gesellschaft für Nuklearmedizin (DGN) und der Arbeitsgruppe “Nuklearkardiologische Diagnostik” der Deutschen Gesellschaft für Kardiologie, Herz- und Kreislaufforschung (DGK)


 

  • Literatur

  • 1 Schäfers M. Methoden und klinische Anwendung der Nuklearkardiologie: Positionsbericht. Nuklearmedizin 2002; 41: 3-13.
    Thieme ConnectPubMedSearch in Google Scholar
  • 2 Zimmermann R, vom Dahl J, Schäfers M, Schwaiger M. Positionsbericht Nuklearkardiologie. Update. Z Kardiol 2002; 91: 88-92.
    CrossrefPubMedSearch in Google Scholar
  • 3 Schwaiger M. Indikationen für die klinischen anwendung der Positronen-Emissions-Tomographie in der Kardiologie. Positionsbericht der Arbeitsgruppe PET-Kardiologie der Deutschen Gesellschaft für Nuklearmedizin und des Arbeitskreis Nuklearkardiologie der Deutschen Gesellschaft für Kardiologie. Z Kardiol 1996; 85: 453-468.
    Search in Google Scholar
  • 4 Hesse B, Tagil K, Cuocolo A, et al. EANM/ESC procedural guidelines for myocardial perfusion imaging in nuclear cardiology. Eur J Nucl Med Mol Imaging 2005; 32: 855-897.
    CrossrefPubMedSearch in Google Scholar
  • 5 Hesse B, Lindhardt TB, Acampa W. et al. EANM/ ESC guidelines for radionuclide imaging of cardiac function. Eur J Nucl Med Mol Imaging 2008; 35: 851-885.
    CrossrefPubMedSearch in Google Scholar
  • 6 Wittry MD, Juni JE, Royal HD. et al. Procedure guideline for equilibrium radionuclide ventriculo- graphy. society of nuclear medicine. J Nucl Med 1997; 38: 1658-1661.
    PubMedSearch in Google Scholar
  • 7 Klocke FJ, Baird MG, Lorell BH. et al. ACC/AHA/ ASNC guidelines for the clinical use of cardiac radionuclide imaging - executive summary: A report of the american college of Cardiology/American heart association task force on practice guidelines (ACC/AHA/ASNC committee to revise the 1995 guidelines for the clinical use of cardiac radionuclide imaging). J Am Coll Cardiol 2003; 42: 1318-1333.
    CrossrefPubMedSearch in Google Scholar
  • 8 Tilkemeier PL. ASNC Imaging Guidlines for Nuclear Cardiology Procedures: Standardized reporting of myocardial perfusion images. J Nucl Cardiol. 2009 im Druck.
    PubMedSearch in Google Scholar
  • 9 Hansen CL, Goldstein RA, Akinoboboye OO. et al. ASCN Imaging Guidelines for Nuclear Cardiology. Myocardial Perfusion and Function: Single photon emission computed tomography. J Nucl Cardiol 2007; 14: e39-e60.
    CrossrefPubMedSearch in Google Scholar
  • 10 Hendel RC. Attenuation correction: Eternal dilemma or real improvement?. Q J Nucl Med Mol Imaging 2005; 49: 30-42.
    PubMedSearch in Google Scholar
  • 11 Bateman TM, Berman DS, Heller GV. et al. American society of nuclear cardiology position statement on electrocardiographic gating of myocardi- al perfusion SPECT scintigrams. J Nucl Cardiol 1999; 6: 470-471.
    CrossrefPubMedSearch in Google Scholar
  • 12 Buell U, Schwaiger M. Herz, Kreislauf, Gefäße. In: Buell U, Schicha H, Biersack HJ. et al. (eds) Nuklearmedizin. Stuttgart: Georg Thieme; 1999: 208-283.
    Search in Google Scholar
  • 13 Hoer G, Krause BJ, Tillmanns HH. Kardiologische Nuklearmedizin. Landsberg: Ecomed; 1997
    Search in Google Scholar
  • 14 Mead WF. Maximal exercise testing-bruce protocol. J Fam Pract 1979; 9: 479-490.
    PubMedSearch in Google Scholar
  • 15 Gaul G. Stress testing in persons above the age of 65 years: Applicability and diagnostic value of a standardized maximal symptom-limited testing protocol. Eur Heart J 1984; 5 (Suppl E) 51-53.
    PubMedSearch in Google Scholar
  • 16 Myers J, Froelicher VF. Exercise testing. procedures and implementation. Cardiol Clin 1993; 11: 199-213.
    PubMedSearch in Google Scholar
  • 17 Lear SA, Brozic A, Myers JN, Ignaszewski A. Exercise stress testing. an overview of current guidelines. Sports Med 1999; 27: 285-312.
    PubMedSearch in Google Scholar
  • 18 Lollgen H, Ulmer HV, Crean P. Recommendations and standard guidelines for exercise testing. report of the task force conference on ergometry, titisee 1987. Eur Heart J 1988; 9 (Suppl K) 3-37.
    PubMedSearch in Google Scholar
  • 19 Iskandrian AS, Heo J, Kong B, Lyons E. Effect of exercise level on the ability of thallium-201 tomo- graphic imaging in detecting coronary artery disease: Analysis of 461 patients. J Am Coll Cardiol 1989; 14: 1477-1486.
    CrossrefPubMedSearch in Google Scholar
  • 20 Lette J, Tatum JL, Fraser S. et al. Safety of dipyridamole testing in 73,806 patients: The multicenter dipyridamole safety study. J Nucl Cardiol 1995; 2: 3-17.
    CrossrefPubMedSearch in Google Scholar
  • 21 Cerqueira MD, Verani MS, Schwaiger M. et al. Safety profile of adenosine stress perfusion imaging: Results from the adenoscan multicenter trial registry. J Am Coll Cardiol 1994; 23: 384-389.
    CrossrefPubMedSearch in Google Scholar
  • 22 Steele P, Sklar J, Kirch D. et al. Thallium-201 myo- cardial imaging during maximal and submaximal exercise: Comparison of submaximal exercise with propranolol. Am Heart J 1983; 106: 1353-1357.
    CrossrefPubMedSearch in Google Scholar
  • 23 Hockings B, Saltissi S, Croft DN, Webb-Peploe MM. Effect of beta adrenergic blockade on thallium-201 myocardial perfusion imaging. Br Heart J 1983; 49: 83-89.
    CrossrefPubMedSearch in Google Scholar
  • 24 Martin GJ, Henkin RE, Scanlon PJ. Beta blockers and the sensitivity of the thallium treadmill test. Chest 1987; 92: 486-487.
    CrossrefPubMedSearch in Google Scholar
  • 25 Zacca NM, Verani MS, Chahine RA, Miller RR. Effect ofnifedipine on exercise-induced left ventricular dysfunction and myocardial hypoperfusion in stable angina. Am J Cardiol 1982; 50: 689-695.
    CrossrefPubMedSearch in Google Scholar
  • 26 Aoki M, Sakai K, Koyanagi S. et al. Effect of nitro-glycerin on coronary collateral function during exercise evaluated by quantitative analysis of thallium-201 single photon emission computed tomography. Am Heart J 1991; 121: 1361-1366.
    CrossrefPubMedSearch in Google Scholar
  • 27 Esquivel L, Pollock SG, Beller GA. et al. Effect of the degree of effort on the sensitivity of the exercise thallium-201 stress test in symptomatic coronary artery disease. Am J Cardiol 1989; 63: 160-165.
    CrossrefPubMedSearch in Google Scholar
  • 28 Altehoefer C, vom Dahl J, Bares R. et al. Metabolic mismatch of septal beta-oxidation and glucose utilization in left bundle branch block assessed with PET. J Nucl Med 1995; 36: 2056-2059.
    PubMedSearch in Google Scholar
  • 29 Burns RJ, Galligan L, Wright LM. et al. Improved specificity of myocardial thallium-201 singlephoton emission computed tomography in patients with left bundle branch block by dipyrida- mole. Am J Cardiol 1991; 68: 504-508.
    CrossrefPubMedSearch in Google Scholar
  • 30 Rockett JF, Wood WC, Moinuddin M. et al. Intravenous dipyridamole thallium-201 SPECT imaging in patients with left bundle branch block. Clin Nucl Med 1990; 15: 401-407.
    CrossrefPubMedSearch in Google Scholar
  • 31 O'Keefe Jr JH, Bateman TM, Silvestri R, Barnhart C. Safety and diagnostic accuracy of adenosine thallium-201 scintigraphy in patients unable to exercise and those with left bundle branch block. Am Heart J 1992; 124: 614-621.
    CrossrefPubMedSearch in Google Scholar
  • 32 Zanco P, Desideri A, Mobilia G. et al. Effects of left bundle branch block on myocardial FDG PET in patients without significant coronary artery stenoses. J Nucl Med 2000; 41: 973-977.
    PubMedSearch in Google Scholar
  • 33 Maddahi J, Berman DS. Reverse redistribution of thallium-201. J Nucl Med 1995; 36: 1019-1021.
    PubMedSearch in Google Scholar
  • 34 Soufer R, Dey HM, Lawson AJ. et al. Relationship between reverse redistribution on planar thallium scintigraphy and regional myocardial viability: A correlative PET study. J Nucl Med 1995; 36: 180-187.
    PubMedSearch in Google Scholar
  • 35 Hariharan R, Bray M, Ganim R. et al. Fundamental limitations of [18F]2-deoxy-2-fluoro-D-glucose for assessing myocardial glucose uptake. Circulation 1995; 91: 2435-2444.
    CrossrefPubMedSearch in Google Scholar
  • 36 Knuuti MJ, Nuutila P, Ruotsalainen U. et al. Eugly- cemic hyperinsulinemic clamp and oral glucose load in stimulating myocardial glucose utilization during positron emission tomography. J Nucl Med 1992; 33: 1255-1262.
    PubMedSearch in Google Scholar
  • 37 Bax JJ, Veening MA, Visser FC. et al. Optimal metabolic conditions during fluorine-18 fluorode-oxyglucose imaging; a comparative study using different protocols. Eur J Nucl Med 1997; 24: 35-41.
    CrossrefPubMedSearch in Google Scholar
  • 38 Patlak CS, Blasberg RG. Graphical evaluation of blood-to-brain transfer constants from multiple- time uptake data. generalizations. J Cereb Blood Flow Metab 1985; 5: 584-590.
    PubMedSearch in Google Scholar
  • 39 Gambhir SS, Schwaiger M, Huang SC. et al. Simple noninvasive quantification method for measuring myocardial glucose utilization in humans employing positron emission tomography and fluori- ne-18 deoxyglucose. J Nucl Med 1989; 30: 359-366.
    PubMedSearch in Google Scholar
  • 40 Ohtake T, Kosaka N, Watanabe T. et al. Noninvasive method to obtain input function for measuring tissue glucose utilization of thoracic and abdominal organs. J Nucl Med 1991; 32: 1432-1438.
    PubMedSearch in Google Scholar
  • 41 Merlet P, Valette H, Dubois-Rande JL. et al. Iodine 123-labeled metaiodobenzylguanidine imaging in heart disease. J Nucl Cardiol 1994; 1: S79-85.
    CrossrefPubMedSearch in Google Scholar
  • 42 Schäfers M, Schober O, Lerch H. Cardiac sympathetic neurotransmission scintigraphy. Eur J Nucl Med 1998; 25: 435-441.
    CrossrefPubMedSearch in Google Scholar
  • 43 Clausen M. et al. Arbeitsgemeinschaft Standardisierung. Allgemeine empfehlungen zur standardisierten bilddokumentation. Nuklearmedizin 1997; 36: 53-54.
    Search in Google Scholar
  • 44 Standardization of cardiac tomographic imaging. the cardiovascular imaging committee, american college of cardiology; the committee on advanced cardiac imaging and technology, council on clinical cardiology, american heart association; and board of directors, cardiovascular council, society of nuclear medicine. J Am Coll Cardiol 1992; 20: 255-256.
    CrossrefPubMedSearch in Google Scholar
  • 45 Cerqueira MD, Weissman NJ, Dilsizian V. et al. Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart. A statement for healthcare professionals from the cardiac imaging committee of the council on clinical cardiology of the american heart association. Int J Cardiovasc Imaging 2002; 18: 539-542.
    PubMedSearch in Google Scholar
  • 46 Leslie WD, Tully SA, Yogendran MS. et al. Prognostic value of automated quantification of 99mTc-sestamibi myocardial perfusion imaging. J Nucl Med 2005; 46: 204-211.
    PubMedSearch in Google Scholar
  • 47 DePuey EG, Nichols K, Dobrinsky C. Left ventricular ejection fraction assessed from gated tech- netium-99m-sestamibi SPECT. J Nucl Med 1993; 34: 1871-1876.
    PubMedSearch in Google Scholar
  • 48 Iskandrian AE, Germano G, van Decker W. et al. Validation of left ventricular volume measurements by gated SPECT 99mTc-labeled sestamibi imaging. J Nucl Cardiol 1998; 5: 574-578.
    CrossrefPubMedSearch in Google Scholar
  • 49 Biedenstein S, Schafers M, Stegger L. et al. Three- dimensional contour detection of left ventricular myocardium using elastic surfaces. Eur J Nucl Med 1999; 26: 201-207.
    CrossrefPubMedSearch in Google Scholar
  • 50 Imaging guidelines for nuclear cardiology procedures, part 2. american society of nuclear cardiology. J Nucl Cardiol 1999; 6: G47-G84.
    CrossrefPubMedSearch in Google Scholar
  • 51 Hendel RC, Wackers FJ, Berman DS. et al. American society of nuclear cardiology consensus statement: Reporting of radionuclide myocardial perfusion imaging studies. J Nucl Cardiol 2003; 10: 705-708.
    CrossrefPubMedSearch in Google Scholar
  • 52 ICRP publication 62. radiological protection in biomedical research. Annals of the IRCP Vol. 22/4. Pregamon Press; 1993
    Search in Google Scholar
  • 53 ICRP publication 80. radiation dose to patients from radioparmaceuticals. Annals of the IRCP Vol. 28/3. Pregamon Press; 1998
    Search in Google Scholar
  • 54 Johansson L. Hormesis, an update of the present position. Eur J Nucl Med Mol Imaging 2003; 30: 921-933.
    CrossrefPubMedSearch in Google Scholar
  • 55 Feinendegen LE. Evidence for beneficial low level radiation effects and radiation hormesis. Br J Radiol 2005; 78: 3-7.
    CrossrefPubMedSearch in Google Scholar
  • 56 Bundesamt für Strahlenschutz
  • 57 Kranert WT, Hör G. Strahlenexposition bei herzuntersuchungen. In: Hör G, Krause BJ, Tillmann HH. (Hrsg) Kardiologische Nuklearmedizin. Landsberg: Ecomed; 1997
    Search in Google Scholar
  • 58 Schober O, Lottes G. Positron emission tomography and radiation exposure. Nuklearmedizin 1994; 33: 174-177.
    Thieme ConnectPubMedSearch in Google Scholar
  • 59 Des Prez RD, Shaw LJ, Gillespie RL. et al. Cost-effectiveness of myocardial perfusion imaging: A summary of the currently available literature. J Nucl Cardiol 2005; 12: 750-759.
    CrossrefPubMedSearch in Google Scholar
  • 60 Shaw LJ, Hachamovitch R, Heller GV. et al. Noninvasive strategies for the estimation of cardiac risk in stable chest pain patients. the economics of noninvasive diagnosis (END) study group. Am J Cardiol 2000; 86: 1-7.
    Search in Google Scholar
  • 61 Giri S, Shaw LJ, Murthy DR. et al. Impact of diabetes on the risk stratification using stress singlephoton emission computed tomography myocar- dial perfusion imaging in patients with symptoms suggestive of coronary artery disease. Circulation 2002; 105: 32-40.
    CrossrefPubMedSearch in Google Scholar
  • 62 Shaw LJ, Hachamovitch R, Berman DS. et al. The economic consequences of available diagnostic and prognostic strategies for the evaluation of stable angina patients: An observational assessment of the value of precatheterization ischemia. economics ofnoninvasive diagnosis (END) multicenter study group. J Am Coll Cardiol 1999; 33: 661-669.
    Search in Google Scholar
  • 63 Underwood SR, Godman B, Salyani S. et al. Economics of myocardial perfusion imaging in europe - the EMPIRE study. Eur Heart J 1999; 20: 157-166.
    CrossrefPubMedSearch in Google Scholar