Position paper nuclear cardiology: Update 2008

M. Schäfers; F. Bengel; U. Büll; W. Burchert; P. Kies; R. Kluge; B. J. Krause; O. Lindner; C. Nienaber; B. Nowak; W. Schäfer; O. Schober; M. Schwaiger; S. Silber; L. Stegger; J. vom Dahl; R. Zimmermann

doi:10.3413/nukmed-0220

Nuklearmedizin - NuclearMedicine, Table of Contents

Nuklearmedizin 2009; 48(02): 71-78
DOI: 10.3413/nukmed-0220

Positionspapier Nuklearkardiologie

Schattauer GmbH

Position paper nuclear cardiology: Update 2008

State-of-the-art of scintigraphic methodsPositionspapier Nuklear kardiologie: Update 2008Aktueller Stand der szintigraphischen Methodik

M. Schäfers^*

¹Klinik und Poliklinik für Nuklearmedizin, Universitätsklinikum Münster

,

F. Bengel^*

²Cardiovascular Nuclear Medicine, Johns Hopkins University Medical Institutions, Baltimore, USA

,

U. Büll^*

³Klinik und Poliklinik für Nuklearmedizin, UK Aachen

,

W. Burchert^*

⁴Institut für Radiologie, Nuklearmedizin und Molekulare Bildgebung, Herz- und Diabeteszentrum NRW, Universitätsklinik der Ruhr-Universität Bochum, Bad Oeynhausen

,

P. Kies^*

¹Klinik und Poliklinik für Nuklearmedizin, Universitätsklinikum Münster

,

R. Kluge^*

⁵Klinik und Poliklinik für Nuklearmedizin, UK Leipzig

,

B. J. Krause^*

⁷Nuklearmedizinische Klinik und Poliklinik, TU München

,

O. Lindner^*

⁴Institut für Radiologie, Nuklearmedizin und Molekulare Bildgebung, Herz- und Diabeteszentrum NRW, Universitätsklinik der Ruhr-Universität Bochum, Bad Oeynhausen

,

C. Nienaber^*

⁶Klinik und Poliklinik für Innere Medizin – Kardiologie, Klinikum der Universität Rostock

,

B. Nowak^*

³Klinik und Poliklinik für Nuklearmedizin, UK Aachen

,

W. Schäfer^*

³Klinik und Poliklinik für Nuklearmedizin, UK Aachen

,

O. Schober^*

¹Klinik und Poliklinik für Nuklearmedizin, Universitätsklinikum Münster

,

M. Schwaiger^*

⁷Nuklearmedizinische Klinik und Poliklinik, TU München

,

S. Silber^*

⁸Kardiologische Gemeinschaftspraxis und Praxisklinik in der Klinik Dr. Müller, München

,

L. Stegger^*

¹Klinik und Poliklinik für Nuklearmedizin, Universitätsklinikum Münster

,

J. vom Dahl^*

⁹Kliniken Maria Hilf GmbH, Klinik für Kardiologie, Mönchengladbach

,

R. Zimmermann^*

¹⁰Medizinische Klinik I – Kardiologie, Klinikum Pforzheim

› Author Affiliations

Abstract

Summary

Nuclear cardiology is well established in clinical diagnostic algorithms for many years. This is an update 2008 of the first common position paper of the German Association of Nuclear Medicine and the German Association of Cardiology, Heart and Circulation Research published in 2001 aiming at an overview of state-of-the-art scintigraphic methods.

Zusammenfassung

Die nuklearkardiologischen Verfahren besitzen seit langem einen festen klinischen Stellenwert. Das “Update 2008” des 2001 erstmals verfassten Positionspapieres der Deutschen Gesellschaft für Nuklearmedizin und der Deutschen Gesellschaft für Kardiologie, Herz- und Kreislaufforschung bietet einen aktuellen Überblick Über die szintigraphische Methodik.

Keywords

Position paper - nuclear cardiology - myocardial scintigraphy - SPECT - PET

Schlüsselwörter

Positionspapier - Nuklearkardiologie - Myokardszintigraphie - SPECT - PET

Full Text

References

Literatur
1 Schäfers M. Methoden und klinische Anwendung der Nuklearkardiologie: Positionsbericht. Nuklearmedizin 2002; 41: 3-13.
2 Zimmermann R, vom Dahl J, Schäfers M, Schwaiger M. Positionsbericht Nuklearkardiologie. Update. Z Kardiol 2002; 91: 88-92.
3 Schwaiger M. Indikationen für die klinischen anwendung der Positronen-Emissions-Tomographie in der Kardiologie. Positionsbericht der Arbeitsgruppe PET-Kardiologie der Deutschen Gesellschaft für Nuklearmedizin und des Arbeitskreis Nuklearkardiologie der Deutschen Gesellschaft für Kardiologie. Z Kardiol 1996; 85: 453-468.
4 Hesse B, Tagil K, Cuocolo A, et al. EANM/ESC procedural guidelines for myocardial perfusion imaging in nuclear cardiology. Eur J Nucl Med Mol Imaging 2005; 32: 855-897.
5 Hesse B, Lindhardt TB, Acampa W. et al. EANM/ ESC guidelines for radionuclide imaging of cardiac function. Eur J Nucl Med Mol Imaging 2008; 35: 851-885.
6 Wittry MD, Juni JE, Royal HD. et al. Procedure guideline for equilibrium radionuclide ventriculo- graphy. society of nuclear medicine. J Nucl Med 1997; 38: 1658-1661.
7 Klocke FJ, Baird MG, Lorell BH. et al. ACC/AHA/ ASNC guidelines for the clinical use of cardiac radionuclide imaging - executive summary: A report of the american college of Cardiology/American heart association task force on practice guidelines (ACC/AHA/ASNC committee to revise the 1995 guidelines for the clinical use of cardiac radionuclide imaging). J Am Coll Cardiol 2003; 42: 1318-1333.
8 Tilkemeier PL. ASNC Imaging Guidlines for Nuclear Cardiology Procedures: Standardized reporting of myocardial perfusion images. J Nucl Cardiol. 2009 im Druck.
9 Hansen CL, Goldstein RA, Akinoboboye OO. et al. ASCN Imaging Guidelines for Nuclear Cardiology. Myocardial Perfusion and Function: Single photon emission computed tomography. J Nucl Cardiol 2007; 14: e39-e60.
10 Hendel RC. Attenuation correction: Eternal dilemma or real improvement?. Q J Nucl Med Mol Imaging 2005; 49: 30-42.
11 Bateman TM, Berman DS, Heller GV. et al. American society of nuclear cardiology position statement on electrocardiographic gating of myocardi- al perfusion SPECT scintigrams. J Nucl Cardiol 1999; 6: 470-471.
12 Buell U, Schwaiger M. Herz, Kreislauf, Gefäße. In: Buell U, Schicha H, Biersack HJ. et al. (eds) Nuklearmedizin. Stuttgart: Georg Thieme; 1999: 208-283.
13 Hoer G, Krause BJ, Tillmanns HH. Kardiologische Nuklearmedizin. Landsberg: Ecomed; 1997
14 Mead WF. Maximal exercise testing-bruce protocol. J Fam Pract 1979; 9: 479-490.
15 Gaul G. Stress testing in persons above the age of 65 years: Applicability and diagnostic value of a standardized maximal symptom-limited testing protocol. Eur Heart J 1984; 5 (Suppl E) 51-53.
16 Myers J, Froelicher VF. Exercise testing. procedures and implementation. Cardiol Clin 1993; 11: 199-213.
17 Lear SA, Brozic A, Myers JN, Ignaszewski A. Exercise stress testing. an overview of current guidelines. Sports Med 1999; 27: 285-312.
18 Lollgen H, Ulmer HV, Crean P. Recommendations and standard guidelines for exercise testing. report of the task force conference on ergometry, titisee 1987. Eur Heart J 1988; 9 (Suppl K) 3-37.
19 Iskandrian AS, Heo J, Kong B, Lyons E. Effect of exercise level on the ability of thallium-201 tomo- graphic imaging in detecting coronary artery disease: Analysis of 461 patients. J Am Coll Cardiol 1989; 14: 1477-1486.
20 Lette J, Tatum JL, Fraser S. et al. Safety of dipyridamole testing in 73,806 patients: The multicenter dipyridamole safety study. J Nucl Cardiol 1995; 2: 3-17.
21 Cerqueira MD, Verani MS, Schwaiger M. et al. Safety profile of adenosine stress perfusion imaging: Results from the adenoscan multicenter trial registry. J Am Coll Cardiol 1994; 23: 384-389.
22 Steele P, Sklar J, Kirch D. et al. Thallium-201 myo- cardial imaging during maximal and submaximal exercise: Comparison of submaximal exercise with propranolol. Am Heart J 1983; 106: 1353-1357.
23 Hockings B, Saltissi S, Croft DN, Webb-Peploe MM. Effect of beta adrenergic blockade on thallium-201 myocardial perfusion imaging. Br Heart J 1983; 49: 83-89.
24 Martin GJ, Henkin RE, Scanlon PJ. Beta blockers and the sensitivity of the thallium treadmill test. Chest 1987; 92: 486-487.
25 Zacca NM, Verani MS, Chahine RA, Miller RR. Effect ofnifedipine on exercise-induced left ventricular dysfunction and myocardial hypoperfusion in stable angina. Am J Cardiol 1982; 50: 689-695.
26 Aoki M, Sakai K, Koyanagi S. et al. Effect of nitro-glycerin on coronary collateral function during exercise evaluated by quantitative analysis of thallium-201 single photon emission computed tomography. Am Heart J 1991; 121: 1361-1366.
27 Esquivel L, Pollock SG, Beller GA. et al. Effect of the degree of effort on the sensitivity of the exercise thallium-201 stress test in symptomatic coronary artery disease. Am J Cardiol 1989; 63: 160-165.
28 Altehoefer C, vom Dahl J, Bares R. et al. Metabolic mismatch of septal beta-oxidation and glucose utilization in left bundle branch block assessed with PET. J Nucl Med 1995; 36: 2056-2059.
29 Burns RJ, Galligan L, Wright LM. et al. Improved specificity of myocardial thallium-201 singlephoton emission computed tomography in patients with left bundle branch block by dipyrida- mole. Am J Cardiol 1991; 68: 504-508.
30 Rockett JF, Wood WC, Moinuddin M. et al. Intravenous dipyridamole thallium-201 SPECT imaging in patients with left bundle branch block. Clin Nucl Med 1990; 15: 401-407.
31 O'Keefe Jr JH, Bateman TM, Silvestri R, Barnhart C. Safety and diagnostic accuracy of adenosine thallium-201 scintigraphy in patients unable to exercise and those with left bundle branch block. Am Heart J 1992; 124: 614-621.
32 Zanco P, Desideri A, Mobilia G. et al. Effects of left bundle branch block on myocardial FDG PET in patients without significant coronary artery stenoses. J Nucl Med 2000; 41: 973-977.
33 Maddahi J, Berman DS. Reverse redistribution of thallium-201. J Nucl Med 1995; 36: 1019-1021.
34 Soufer R, Dey HM, Lawson AJ. et al. Relationship between reverse redistribution on planar thallium scintigraphy and regional myocardial viability: A correlative PET study. J Nucl Med 1995; 36: 180-187.
35 Hariharan R, Bray M, Ganim R. et al. Fundamental limitations of [¹⁸F]2-deoxy-2-fluoro-D-glucose for assessing myocardial glucose uptake. Circulation 1995; 91: 2435-2444.
36 Knuuti MJ, Nuutila P, Ruotsalainen U. et al. Eugly- cemic hyperinsulinemic clamp and oral glucose load in stimulating myocardial glucose utilization during positron emission tomography. J Nucl Med 1992; 33: 1255-1262.
37 Bax JJ, Veening MA, Visser FC. et al. Optimal metabolic conditions during fluorine-18 fluorode-oxyglucose imaging; a comparative study using different protocols. Eur J Nucl Med 1997; 24: 35-41.
38 Patlak CS, Blasberg RG. Graphical evaluation of blood-to-brain transfer constants from multiple- time uptake data. generalizations. J Cereb Blood Flow Metab 1985; 5: 584-590.
39 Gambhir SS, Schwaiger M, Huang SC. et al. Simple noninvasive quantification method for measuring myocardial glucose utilization in humans employing positron emission tomography and fluori- ne-18 deoxyglucose. J Nucl Med 1989; 30: 359-366.
40 Ohtake T, Kosaka N, Watanabe T. et al. Noninvasive method to obtain input function for measuring tissue glucose utilization of thoracic and abdominal organs. J Nucl Med 1991; 32: 1432-1438.
41 Merlet P, Valette H, Dubois-Rande JL. et al. Iodine 123-labeled metaiodobenzylguanidine imaging in heart disease. J Nucl Cardiol 1994; 1: S79-85.
42 Schäfers M, Schober O, Lerch H. Cardiac sympathetic neurotransmission scintigraphy. Eur J Nucl Med 1998; 25: 435-441.
43 Clausen M. et al. Arbeitsgemeinschaft Standardisierung. Allgemeine empfehlungen zur standardisierten bilddokumentation. Nuklearmedizin 1997; 36: 53-54.
44 Standardization of cardiac tomographic imaging. the cardiovascular imaging committee, american college of cardiology; the committee on advanced cardiac imaging and technology, council on clinical cardiology, american heart association; and board of directors, cardiovascular council, society of nuclear medicine. J Am Coll Cardiol 1992; 20: 255-256.
45 Cerqueira MD, Weissman NJ, Dilsizian V. et al. Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart. A statement for healthcare professionals from the cardiac imaging committee of the council on clinical cardiology of the american heart association. Int J Cardiovasc Imaging 2002; 18: 539-542.
46 Leslie WD, Tully SA, Yogendran MS. et al. Prognostic value of automated quantification of ^99mTc-sestamibi myocardial perfusion imaging. J Nucl Med 2005; 46: 204-211.
47 DePuey EG, Nichols K, Dobrinsky C. Left ventricular ejection fraction assessed from gated tech- netium-99m-sestamibi SPECT. J Nucl Med 1993; 34: 1871-1876.
48 Iskandrian AE, Germano G, van Decker W. et al. Validation of left ventricular volume measurements by gated SPECT ^99mTc-labeled sestamibi imaging. J Nucl Cardiol 1998; 5: 574-578.
49 Biedenstein S, Schafers M, Stegger L. et al. Three- dimensional contour detection of left ventricular myocardium using elastic surfaces. Eur J Nucl Med 1999; 26: 201-207.
50 Imaging guidelines for nuclear cardiology procedures, part 2. american society of nuclear cardiology. J Nucl Cardiol 1999; 6: G47-G84.
51 Hendel RC, Wackers FJ, Berman DS. et al. American society of nuclear cardiology consensus statement: Reporting of radionuclide myocardial perfusion imaging studies. J Nucl Cardiol 2003; 10: 705-708.
52 ICRP publication 62. radiological protection in biomedical research. Annals of the IRCP Vol. 22/4. Pregamon Press; 1993
53 ICRP publication 80. radiation dose to patients from radioparmaceuticals. Annals of the IRCP Vol. 28/3. Pregamon Press; 1998
54 Johansson L. Hormesis, an update of the present position. Eur J Nucl Med Mol Imaging 2003; 30: 921-933.
55 Feinendegen LE. Evidence for beneficial low level radiation effects and radiation hormesis. Br J Radiol 2005; 78: 3-7.
56 Bundesamt für Strahlenschutz
57 Kranert WT, Hör G. Strahlenexposition bei herzuntersuchungen. In: Hör G, Krause BJ, Tillmann HH. (Hrsg) Kardiologische Nuklearmedizin. Landsberg: Ecomed; 1997
58 Schober O, Lottes G. Positron emission tomography and radiation exposure. Nuklearmedizin 1994; 33: 174-177.
59 Des Prez RD, Shaw LJ, Gillespie RL. et al. Cost-effectiveness of myocardial perfusion imaging: A summary of the currently available literature. J Nucl Cardiol 2005; 12: 750-759.
60 Shaw LJ, Hachamovitch R, Heller GV. et al. Noninvasive strategies for the estimation of cardiac risk in stable chest pain patients. the economics of noninvasive diagnosis (END) study group. Am J Cardiol 2000; 86: 1-7.
61 Giri S, Shaw LJ, Murthy DR. et al. Impact of diabetes on the risk stratification using stress singlephoton emission computed tomography myocar- dial perfusion imaging in patients with symptoms suggestive of coronary artery disease. Circulation 2002; 105: 32-40.
62 Shaw LJ, Hachamovitch R, Berman DS. et al. The economic consequences of available diagnostic and prognostic strategies for the evaluation of stable angina patients: An observational assessment of the value of precatheterization ischemia. economics ofnoninvasive diagnosis (END) multicenter study group. J Am Coll Cardiol 1999; 33: 661-669.
63 Underwood SR, Godman B, Salyani S. et al. Economics of myocardial perfusion imaging in europe - the EMPIRE study. Eur Heart J 1999; 20: 157-166.