Vet Comp Orthop Traumatol 2015; 28(01): 30-38
DOI: 10.3415/VCOT-14-05-0076
Original Research
Schattauer GmbH

Negative pressure wound therapy, silver coated foam dressing and conventional bandages in open wound treatment in dogs

A retrospective comparison of 50 paired cases
M. C. Nolff
1   Ludwig-Maximilians University, Clinic for Small Animal Surgery and Reproduction, Munich, Germany
,
M. Fehr
2   University of Veterinary Medicine Hanover, Foundation, Small Animal Clinic, Hanover, Germany
,
A. Bolling
2   University of Veterinary Medicine Hanover, Foundation, Small Animal Clinic, Hanover, Germany
,
R. Dening
2   University of Veterinary Medicine Hanover, Foundation, Small Animal Clinic, Hanover, Germany
,
S. Kramer
2   University of Veterinary Medicine Hanover, Foundation, Small Animal Clinic, Hanover, Germany
,
S. Reese
3   Ludwig-Maximilians University, Department for Basic Veterinary Sciences, Munich, Germany
,
A. Meyer-Lindenberg
1   Ludwig-Maximilians University, Clinic for Small Animal Surgery and Reproduction, Munich, Germany
› Institutsangaben
Weitere Informationen

Publikationsverlauf

Received:21. Mai 2014

Accepted:06. November 2014

Publikationsdatum:
26. Dezember 2017 (online)

Summary

Objectives: To evaluate negative pressure wound therapy (NPWT) for treatment of complicated wounds in dogs.

Study type: Retrospective multicentre study.

Materials and methods: Dogs (n = 50) undergoing open wound treatment were classified according to treatment method used: bandage (Group A, n = 7), NPWT (Group B, n = 18), and foam dressing (Group C, n = 25). Pairs of patients matched based on wound conformation, localization, and underlying cause were compared between Group A and C (n = 7 pairs) and between groups B and C (n = 18 pairs) in terms of duration of previous treatment, time to closure, and complications.

Results: Signalment, antibiotic medications, antiseptic treatment, and bacterial status of wounds were comparable between groups. The duration of previous treatment was significantly higher in patients assigned to Group B (p = 0.04) compared to Group C, while no significant difference was found between groups A and B. Total time to wound closure was significantly shorter in Group C compared to Group A (p = 0.02) and in Group B compared to Group C (p = 0.003). Wounds treated with NPWT suffered significantly less complications (p = 0.008) and were significantly less septic during treatment (p = 0.016) than wounds treated with a foam dressing.

Conclusion: This study shows that time to healing was halved in NPWT treated patients compared to foam dressing treated patients, which in turn healed faster than patients treated with conventional bandage, underlining the value of NPWT therapy for the treatment of complicated wounds.

 
  • References

  • 1 Rozhdestvin VA, Nurgaliev TN, Kiverov SV. [Vacuum-aspiration in the treatment of stab wounds of soft tissues]. Ortop Traumatol Protez 1987; 32.
  • 2 Voinchet V, Magalon G. [Vacuum assisted closure. Wound healing by negative pressure]. Ann Chir Plast Esthet 1996; c41: 583-589.
  • 3 Morykwas MJ, Argenta LC, Shelton-Brown EI. et al. Vacuum-assisted closure: a new method for wound control and treatment: animal studies and basic foundation. Ann Plast Surg 1997; 38: 553-562.
  • 4 Isago T, Nozaki M, Kikuchi Y. et al. Effects of different negative pressures on reduction of wounds in negative pressure dressings. J Dermatol 2003; 30: 596-601.
  • 5 Jones SM, Banwell PE, Shakespeare PG. Advances in wound healing: topical negative pressure therapy. Postgrad Med J 2005; 81: 353-357.
  • 6 Argenta LC, Morykwas MJ, Marks MW. et al. Vacuum-assisted closure: state of clinic art. Plast Reconstr Surg 2006; 117: 127S-142S.
  • 7 Banwell P, Teot L. Topical negative pressure (TNP): the evolution of a novel wound therapy. J Tissue Viability 2006; 16: 16-24.
  • 8 Wackenfors A, Gustafsson R, Sjogren J. et al. Blood flow responses in the peristernal thoracic wall during vacuum-assisted closure therapy. Ann Thorac Surg 2005; 79: 1724-1730. discussion 1730-1721
  • 9 Wackenfors A, Sjogren J, Gustafsson R. et al. Effects of vacuum-assisted closure therapy on inguinal wound edge microvascular blood flow. Wound Repair Regen 2004; 12: 600-606.
  • 10 McNulty AK, Schmidt M, Feeley T. et al. Effects of negative pressure wound therapy on fibroblast viability, chemotactic signaling, and proliferation in a provisional wound (fibrin) matrix. Wound Repair Regen 2007; 15: 838-846.
  • 11 Bertran J, Farrell M, Fitzpatrick N. Successful wound healing over exposed metal implants using vacuum-assisted wound closure in a dog. J Small Anim Pract 2013; 54: 381-385.
  • 12 Bristow PC, Perry KL, Halfacree ZJ. et al. Use of vacuum-assisted closure to maintain viability of a skin flap in a dog. J Am Vet Med Assoc 2013; 243: 863-868.
  • 13 Buote NJ, Havig ME. The use of vacuum-assisted closure in the management of septic peritonitis in six dogs. J Am Anim Hosp assoc 2012; 48: 164-171.
  • 14 Cioffi KM, Schmiedt CW, Cornell KK. et al. Retrospective evaluation of vacuum assisted peritoneal drainage for the treatment of septic peritonitis in dogs and cats: 8 cases (2003-2010). J Vet Emerg Crit Care 2012; 22: 601-609.
  • 15 Kirkby KA, Wheeler J, Farese J. et al. Surgical views: Vacuum-assisted wound closure: clinical applications. Compend Contin Educ Vet 2010; 32: E1-6. quiz E7
  • 16 Kirkby KA, Wheeler J, Farese J. et al. Surgical views: Vacuum-assisted wound closure: application and mechanism of action. Compend Contin Educ Vet 2009; 31: E1-5. quiz E6
  • 17 Owen L, Hotston-Moore A, Holt P. Vacuum-assisted wound closure following urine-induced skin and thigh muscle necrosis in a cat. Vet Comp Orthop Traumatol 2009; 22: 417-421.
  • 18 Mullally C, Carey K, Seshadri R. Use of a nanocrystalline silver dressing and vacuum-assisted closure in a severely burned dog. J Vet Emerg Crit Care 2010; 20: 456-463.
  • 19 Guille AE, Tseng LW, Orsher RJ. Use of vacuum-assisted closure for management of a large skin wound in a cat. J Am Vet Med Assoc 2007; 230: 1669-1673.
  • 20 Ben-Amotz R, Lanz OI, Miller JM. et al. The use of vacuum assisted closure therapy for the treatment of distal extremity wounds in 15 dogs. Vet Surg 2007; 36: 684-690.
  • 21 Demaria M, Stanley BJ, Hauptman JG. et al. Effects of negative pressure wound therapy on healing of open wounds in dogs. Vet Surg 2011; 40: 658-669.
  • 22 Stanley BJ, Pitt KA, Weder CD. et al. Effects of negative pressure wound therapy on healing of free full-thickness skin grafts in dogs. Vet Surg 2013; 42: 511-522.
  • 23 Pitt KA, Stanley BJ. Negative pressure wound therapy: Experience in 45 dogs. Vet Surg 2014; 43: 380-387.
  • 24 Amalsadvala T, Swaim SF. Management of hard to heal wounds. Vet Clin Small Anim 2006; 36: 693-711.
  • 25 Campbell BG. Dressings, bandages, and splints for wound management in dogs and cats. Vet Clin Small Anim 2006; 36: 759-791.
  • 26 Bolton LL, Monte K, Pirone LA. Moisture and healing: beyond the jargon. Ostomy Wound Manage 2000; 46 (Suppl. 01) Suppl A 51-62.
  • 27 Kotz P, Fisher J, McCluskey P. et al. Use of a new silver barrier dressing, ALLEVYN Ag in exuding chronic wounds. Int Wound J 2009; 6: 186-194.
  • 28 Stinner DJ, Waterman SM, Masini BD. et al. Silver dressings augment the ability of negative pressure wound therapy to reduce bacteria in a contaminated open fracture model. J Trauma 2011; 71: S147-150.
  • 29 Percival SL, Thomas J, Linton S. et al. The antimicrobial efficacy of silver on antibiotic-resistant bacteria isolated from burn wounds. Int Wound J 2012; 9: 488-493.
  • 30 Richards AJ, Hagelstein SM, Patel GK. et al. Early use of negative pressure therapy in combination with silver dressings in a difficult breast abscess. Int Wound J 2011; 8: 608-611.
  • 31 Morykwas MJ, Faler BJ, Pearce DJ. et al. Effects of varying levels of subatmospheric pressure on the rate of granulation tissue formation in experimental wounds in swine. Ann Plast Surg 2001; 47: 547-551.
  • 32 Saxena V, Hwang CW, Huang S. et al. Vacuum-assisted closure: microdeformations of wounds and cell proliferation. Plast Reconstr Surg 2004; 114: 1086-1096. discussion 1097-1088
  • 33 Lalliss SJ, Stinner DJ, Waterman SM. et al. Negative pressure wound therapy reduces pseudomonas wound contamination more than Staphylococcus aureus. J Orthop Trauma 2010; 24: 598-602.
  • 34 Weed T, Ratliff C, Drake DB. Quantifying bacterial bioburden during negative pressure wound therapy: does the wound VAC enhance bacterial clearance?. Ann Plast Surg 2004; 52: 276-279.
  • 35 Moues CM, Vos MC, van den Bemd GJ. et al. Bacterial load in relation to vacuum-assisted closure wound therapy: a prospective randomized trial. Wound Repair Regen 2004; 12: 11-17.
  • 36 Moues CM, van den Bemd GJ, Heule F. et al. Comparing conventional gauze therapy to vacuum-assisted closure wound therapy: a prospective randomised trial. J Plast Reconstr Aesthet Surg 2007; 60: 672-681.
  • 37 Blume PA, Walters J, Payne W. et al. Comparison of negative pressure wound therapy using vacuum-assisted closure with advanced moist wound therapy in the treatment of diabetic foot ulcers: a multicenter randomized controlled trial. Diabetes Care 2008; 31: 631-636.