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Vet Comp Orthop Traumatol 2018; 31(02): 083-094
DOI: 10.3415/VCOT-16-12-0169
Original Research
Schattauer GmbH Stuttgart

Clinical Application of 3D-CISS MRI Sequences for Diagnosis and Surgical Planning of Spinal Arachnoid Diverticula and Adhesions in Dogs

Anna Tauro
,
Jelena Jovanovik
,
Colin John Driver
,
Clare Rusbridge
Further Information

Publication History

26 December 2016

09 October 2017

Publication Date:
13 March 2018 (online)

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Abstract

Objective Abnormalities within the spinal arachnoid space are often treated surgically, but they can be challenging to detect with conventional magnetic resonance imaging (MRI) sequences. 3D-CISS sequences are considered superior in evaluating structures surrounded by cerebrospinal fluid (CSF) due to the high signal-to-noise ratio, high contrast-to-noise ratio and intrinsic insensitivity to motion with minimal signal loss due to CSF pulsations. Our objective was to describe findings and advantages in adding 3D-CISS sequences to routine MRI in patients affected by spinal arachnoid diverticula (SAD) or arachnoid adhesions.

Material and Methods This article is a retrospective review of medical records of 19 dogs admitted at Fitzpatrick Referrals between 2013 and 2017 that were diagnosed with SAD and confirmed surgically. Inclusion criterions were the presence of clinical signs compatible with compressive myelopathy and an MRI diagnosis, which included the 3D-CISS sequence. Our database was searched for additional 19 dogs diagnosed with other spinal lesions other than SAD that had the same MR sequences. All MR images were anonymized and evaluated by two assessors.

Conclusion and Clinical Relevance 3D-CISS sequence appears to improve confidence in diagnosing and surgical planning (Mann–Whitney U-test: p < 0.0005), delineating SAD from other changes associated with abnormal CSF hydrodynamics and providing more anatomical details than conventional MRI sequences. The clinical data in combination with imaging findings would limit over interpretation, when concurrent pathology within the arachnoid space is present.

Keywords

gradient echo sequence - 3D-CISS - magnetic resonance imaging - arachnoid web - spinal arachnoid diverticulum

Author Contributions

Conception of study: A. Tauro, J. Jovanovik, C. Driver, C. Rusbridge; Study design: A. Tauro, C. Driver, C. Rusbridge; Acquisition of data: A. Tauro, J. Jovanovik; Data analysis and interpretation: A. Tauro, C. Driver, C. Rusbridge; Drafting and revising of manuscript: A. Tauro, C. Driver, C. Rusbridge; Approval of submitted manuscript: all authors.


 

  • References

  • 1 Webb AA. Intradural spinal arachnoid cyst in a dog. Can Vet J 1999; 40 (08) 588-589
    PubMedGoogle Scholar
  • 2 Gonçalves R, Hammond G, Penderis J. Imaging diagnosis: erroneous localization of spinal arachnoid cyst. Vet Radiol Ultrasound 2008; 49 (05) 460-463
    CrossrefPubMedGoogle Scholar
  • 3 Rylander H, Lipsitz D, Berry WL. , et al. Retrospective analysis of spinal arachnoid cysts in 14 dogs. J Vet Intern Med 2002; 16 (06) 690-696
    CrossrefPubMedGoogle Scholar
  • 4 Gage ED, Hoerlein BF, Bartels JE. Spinal cord compression resulting from a leptomeningeal cyst in the dog. J Am Vet Med Assoc 1968; 152 (11) 1664-1670
    PubMedGoogle Scholar
  • 5 Hashizume CT. Cervical spinal arachnoid cyst in a dog. Can Vet J 2000; 41 (03) 225-227
    PubMedGoogle Scholar
  • 6 Ness MG. Spinal arachnoid cysts in two Shih Tzu littermates. Vet Rec 1998; 142 (19) 515-516
    CrossrefPubMedGoogle Scholar
  • 7 Frykman OF. Spinal arachnoid cyst in four dogs: diagnosis, surgical treatment and follow-up results. J Small Anim Pract 1999; 40 (11) 544-549
    CrossrefPubMedGoogle Scholar
  • 8 Gnirs K, Ruel Y, Blot S. , et al. Spinal subarachnoid cysts in 13 dogs. Vet Radiol Ultrasound 2003; 44 (04) 402-408
    CrossrefPubMedGoogle Scholar
  • 9 Skeen TM, Olby NJ, Muñana KR, Sharp NJ. Spinal arachnoid cysts in 17 dogs. J Am Anim Hosp Assoc 2003; 39 (03) 271-282
    CrossrefPubMedGoogle Scholar
  • 10 Jurina K, Grevel V. Spinal arachnoid pseudocysts in 10 Rottweilers. J Small Anim Pract 2004; 45 (01) 9-15
    CrossrefPubMedGoogle Scholar
  • 11 Sessums KB, Ducote JM. ; American College of Veterinary Radiology. What is your diagnosis? Spinal arachnoid cysts. J Am Vet Med Assoc 2006; 228 (07) 1019-1020
    CrossrefPubMedGoogle Scholar
  • 12 Foss KD, Berry WL. What is your neurologic diagnosis? Spinal arachnoid cysts. J Am Vet Med Assoc 2009; 234 (08) 1009-1011
    CrossrefPubMedGoogle Scholar
  • 13 Seiler GS, Robertson ID, Mai W. , et al. Usefulness of a half-Fourier acquisition single-shot turbo spin-echo pulse sequence in identifying arachnoid diverticula in dogs. Vet Radiol Ultrasound 2012; 53 (02) 157-161
    CrossrefPubMedGoogle Scholar
  • 14 Hans EC, Chaudhari SK. What is your neurologic diagnosis? Spinal arachnoid cyst. J Am Vet Med Assoc 2013; 243 (11) 1537-1539
    CrossrefPubMedGoogle Scholar
  • 15 Flegel T, Müller MK, Truar K, Löffler C, Oechtering G. Thoracolumbar spinal arachnoid diverticula in 5 pug dogs. Can Vet J 2013; 54 (10) 969-973
    PubMedGoogle Scholar
  • 16 Rohdin C, Nyman HT, Wohlsein P, Hultin Jäderlund K. Cervical spinal intradural arachnoid cysts in related, young pugs. J Small Anim Pract 2014; 55 (04) 229-234
    CrossrefPubMedGoogle Scholar
  • 17 Bismuth C, Ferrand FX, Millet M. , et al. Original surgical treatment of thoracolumbar subarachnoid cysts in six chondrodystrophic dogs. Acta Vet Scand 2014; 56: 32
    CrossrefPubMedGoogle Scholar
  • 18 Mauler DA, De Decker S, De Risio L. , et al. Signalment, clinical presentation, and diagnostic findings in 122 dogs with spinal arachnoid diverticula. J Vet Intern Med 2014; 28 (01) 175-181
    CrossrefPubMedGoogle Scholar
  • 19 Cambridge AJ, Bagley RS, Britt LG, Silver GM. Radiographic diagnosis: arachnoid cyst in a dog. Vet Radiol Ultrasound 1997; 38 (06) 434-436
    CrossrefPubMedGoogle Scholar
  • 20 Reardon MA, Raghavan P, Carpenter-Bailey K. , et al. Dorsal thoracic arachnoid web and the “scalpel sign”: a distinct clinical-radiologic entity. AJNR Am J Neuroradiol 2013; 34 (05) 1104-1110
    CrossrefPubMedGoogle Scholar
  • 21 Zhang L, Kholmovski EG, Guo J, Choi SE, Morrell GR, Parker DL. HASTE sequence with parallel acquisition and T2 decay compensation: application to carotid artery imaging. Magn Reson Imaging 2009; 27 (01) 13-22
    CrossrefPubMedGoogle Scholar
  • 22 Pease A, Sullivan S, Olby N. , et al. Value of a single-shot turbo spin-echo pulse sequence for assessing the architecture of the subarachnoid space and the constitutive nature of cerebrospinal fluid. Vet Radiol Ultrasound 2006; 47 (03) 254-259
    CrossrefPubMedGoogle Scholar
  • 23 Roser F, Ebner FH, Danz S. , et al. Three-dimensional constructive interference in steady-state magnetic resonance imaging in syringomyelia: advantages over conventional imaging. J Neurosurg Spine 2008; 8 (05) 429-435
    CrossrefPubMedGoogle Scholar
  • 24 Yamashita Y, Tang Y, Abe Y, Mitsuzaki K, Takahashi M. Comparison of ultrafast half-Fourier single-shot turbo spin-echo sequence with turbo spin-echo sequences for T2-weighted imaging of the female pelvis. J Magn Reson Imaging 1998; 8 (06) 1207-1212
    CrossrefPubMedGoogle Scholar
  • 25 Aydin H, Kizilgoz V, Hekimoglu B. Compared with the conventional MR imaging, do the constructive interference steady state sequence and diffusion weighted imaging aid in the diagnosis of lumbar disc hernias?. Eurasian J Med 2011; 43 (03) 152-161
    CrossrefPubMedGoogle Scholar
  • 26 Patel DM, Tubbs RS, Pate G, Johnston Jr JM, Blount JP. Fast-sequence MRI studies for surveillance imaging in pediatric hydrocephalus. J Neurosurg Pediatr 2014; 13 (04) 440-447
    CrossrefPubMedGoogle Scholar
  • 27 Chavhan GB, Babyn PS, Jankharia BG, Cheng HL, Shroff MM. Steady-state MR imaging sequences: physics, classification, and clinical applications. Radiographics 2008; 28 (04) 1147-1160
    CrossrefPubMedGoogle Scholar
  • 28 Semelka RC, Kelekis NL, Thomasson D, Brown MA, Laub GA. HASTE MR imaging: description of technique and preliminary results in the abdomen. J Magn Reson Imaging 1996; 6 (04) 698-699
    CrossrefPubMedGoogle Scholar
  • 29 Hingwala D, Chatterjee S, Kesavadas C, Thomas B, Kapilamoorthy TR. Applications of 3D CISS sequence for problem solving in neuroimaging. Indian J Radiol Imaging 2011; 21 (02) 90-97
    Article in Thieme ConnectPubMedGoogle Scholar
  • 30 Ramli N, Cooper A, Jaspan T. High resolution CISS imaging of the spine. Br J Radiol 2001; 74 (885) 862-873
    CrossrefPubMedGoogle Scholar
  • 31 Flint G, Rusbridge C. The filling mechanism. In: Syringomyelia: A Disorder of CSF Circulation. Berlin Heidelberg: Springer-Verlag; 2014: 87-101
    Google Scholar
  • 32 Yoshino N, Akimoto H, Yamada I. , et al. Trigeminal neuralgia: evaluation of neuralgic manifestation and site of neurovascular compression with 3D CISS MR imaging and MR angiography. Radiology 2003; 228 (02) 539-545
    CrossrefPubMedGoogle Scholar
  • 33 Gonçalves FG, do Amaral LL. Constructive interference in steady state imaging in the central nervous system. Eur Neurol Rev 2011; 6: 138-142
    PubMedGoogle Scholar
  • 34 Kulkarni M. Constructive interference in steady-state/FIESTA-C clinical applications in neuroimaging. J Med Imaging Radiat Oncol 2011; 55 (02) 183-190
    CrossrefPubMedGoogle Scholar
  • 35 Grünenfelder FI, Weishaupt D, Green R, Steffen F. Magnetic resonance imaging findings in spinal cord infarction in three small breed dogs. Vet Radiol Ultrasound 2005; 46 (02) 91-96
    CrossrefPubMedGoogle Scholar
  • 36 Freeman AC, Platt SR, Kent M, Huguet E, Rusbridge C, Holmes S. Chiari-like malformation and syringomyelia in American Brussels Griffon dogs. J Vet Intern Med 2014; 28 (05) 1551-1559
    CrossrefPubMedGoogle Scholar
  • 37 Fenn J, Drees R, Volk HA, Decker SD. Inter- and intraobserver agreement for diagnosing presumptive ischemic myelopathy and acute noncompressive nucleus pulposus extrusion in dogs using magnetic resonance imaging. Vet Radiol Ultrasound 2016; 57 (01) 33-40
    CrossrefPubMedGoogle Scholar
  • 38 Morisako H, Takami T, Yamagata T, Chokyu I, Tsuyuguchi N, Ohata K. Focal adhesive arachnoiditis of the spinal cord: imaging diagnosis and surgical resolution. J Craniovertebr Junction Spine 2010; 1 (02) 100-106
    CrossrefPubMedGoogle Scholar
  • 39 Sayal PP, Zafar A, Carroll TA. Syringomyelia secondary to “occult” dorsal arachnoid webs: report of two cases with review of literature. J Craniovertebr Junction Spine 2016; 7 (02) 101-104
    CrossrefPubMedGoogle Scholar
  • 40 Fischbein NJ, Dillon WP, Cobbs C, Weinstein PR. The “presyrinx” state: is there a reversible myelopathic condition that may precede syringomyelia?. Neurosurg Focus 2000; 8 (03) E4
    PubMedGoogle Scholar
  • 41 Ikushima I, Korogi Y, Hirai T, Yamashita Y. High-resolution constructive interference in a steady state imaging of cervicothoracic adhesive arachnoiditis. J Comput Assist Tomogr 2007; 31 (01) 143-147
    CrossrefPubMedGoogle Scholar
  • 42 Krings T, Geibprasert S. Spinal dural arteriovenous fistulas. AJNR Am J Neuroradiol 2009; 30 (04) 639-648
    CrossrefPubMedGoogle Scholar