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CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2015; 25(01): 56-59
DOI: 10.4103/0971-3026.150149
Neuroradiology

Clinical, imaging and histopathological features of isolated CNS lymphomatoid granulomatosis

Anil Kumar Patil
Department of Neurological Sciences, Section of Neurology, Christian Medical College, Vellore, Tamil Nadu, India
,
Mathew Alexander
Department of Neurological Sciences, Section of Neurology, Christian Medical College, Vellore, Tamil Nadu, India
,
Bijesh Nair
Department of Neurological Sciences, Section of Neurosurgery, Christian Medical College, Vellore, Tamil Nadu, India
,
Geeta Chacko
Department of Neurological Sciences, Section of Neuropathology, Christian Medical College, Vellore, Tamil Nadu, India
,
Sunithi Mani
Department of Radiology, Christian Medical College, Vellore, Tamil Nadu, India
,
Sniya Sudhakar
Department of Radiology, Christian Medical College, Vellore, Tamil Nadu, India
› Institutsangaben Financial support and sponsorship Nil.
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Abstract

Lymphomatoid granulomatosis is a rare systemic angiocentric/angiodestructive, B cell lymphoproliferative disorder. Central nervous system involvement occurs as part of systemic disease. Isolated central nervous system disease is rare with only few case reports. A 53-year-old male presented with progressive cognitive decline, extrapyramidal features, and altered sensorium with seizures over the last 4 years. His magnetic resonance imaging (MRI) of brain showed multiple small enhancing nodules in subependymal/ependymal regions and along the vessels. Brain biopsy showed atypical lymphohistiocytic infiltrate suggestive of lymphomatoid granulomatosis. There was no evidence of systemic disease; thus, isolated central nervous system lymphomatoid granulomatosis was diagnosed.

Keywords

Lymphomatoid granulomatosis - lympho proliferative disorder - nodular enhancing lesions


Publikationsverlauf

Artikel online veröffentlicht:
30. Juli 2021

© 2015. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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