Imaging for assessment of treatment response in hepatocellular carcinoma: Current update

Koichi Hayano; Sang Ho Lee; Dushyant V Sahani

doi:10.4103/0971-3026.155835

Indian Journal of Radiology and Imaging, Table of Contents

CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2015; 25(02): 121-128
DOI: 10.4103/0971-3026.155835

Imaging in Oncology: Recent Advances

Imaging for assessment of treatment response in hepatocellular carcinoma: Current update

Koichi Hayano

Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts, USA

,

Sang Ho Lee

Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts, USA

,

Dushyant V Sahani

Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts, USA

› Author Affiliations

Abstract

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Abstract

Morphologic methods such as the Response Evaluation Criteria in Solid Tumors (RECIST) are considered as the gold standard for response assessment in the management of cancer. However, with the increasing clinical use of antineoplastic cytostatic agents and locoregional interventional therapies in hepatocellular carcinoma (HCC), conventional morphologic methods are confronting limitations in response assessment. Thus, there is an increasing interest in new imaging methods for response assessment, which can evaluate tumor biology such as vascular physiology, fibrosis, necrosis, and metabolism. In this review, we discuss various novel imaging methods for response assessment and compare them with the conventional ones in HCC.

Keywords

Computed tomography perfusion - diffusion weighted imaging - amic contrast-enhanced magnetic resonance imaging - hepatocellular carcinoma - positron emission tomography

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References

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