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DOI: 10.4103/0971-3026.155879
Concurrent nonfunctional paraganglioma of the retroperitoneum and urinary bladder: A case report with literature review
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Abstract
Paragangliomas are the neuroendocrine tumors which arise from the chromaffin cell. Tumors arising from the adrenal medulla are known as pheochromocytomas, while others originating from the extra-adrenal site are known as extra-adrenal paragangliomas. Paraganglioma can be multifocal which can arise synchronously or metachronously. Paragangliomas are less functionally active than the pheochromocytomas; they secrete noradrenaline and rarely dopamine, while adrenal pheochromocytomas secrete adrenaline or nor-adrenaline. Nonfunctional multifocal paragangliomas are very rare. We report a case of a 45-year-old female with multifocal nonfunctional paragangliomas of the retroperitoneum and urinarybladder which were surgically removed, and the diagnosis was confirmed on histopathology.
Publication History
Article published online:
30 July 2021
© 2015. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).
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References
- 1 Sahdev A, Sohaib A, Monson JP, Grossman AB, Chew SL, Reznek RH. CT and MR imaging of unusual locations of extra-adrenal paragangliomas (pheochromocytomas). EurRadiol 2005;15:85-92.
- 2 Lee KY, Oh YW, Noh HJ, Lee YJ, Yong HS, Kang EY,et al. Extraadrenal paragangliomas of the body: Imaging features. AJR Am J Roentgenol2006;187:492-504.
- 3 HonmaK.Paraganglia of the urinary bladder.An autopsy study. Zentralbl Pathol 1994;139:465-9.
- 4 Xu DF, Chen M, Liu YS, Gao Y, Cui XG.Non-functional paraganglioma of the urinarybladder: A case report.J Med Case Rep2010;4:216.
- 5 Thrasher JB, Rajan RR, Perez LM, Humphrey PA, Anderson EE.Pheochromocytoma of urinary bladder: Contemporary methods of diagnosis and treatment options.Urology 1993;41:435-9.
- 6 Karaçetin D, Halefoðlu A, Kabukçuoðlu F, Tatar Z.Retroperitoneal paragangloma: Case presentation. Istanbul Med J 2010;11:137-141.
- 7 Cronan JJ, Do HM, Monchik JM, Stein BS.Bladder pheochromocytoma.Color Doppler sonographic correlation.J Ultrasound Med 1992;11:493-5.
- 8 Heyman J, Cheung Y, Ghali V, Leiter E. Bladder pheochromocytoma: Evaluation with magnetic resonance imaging.J Urol1989;141:1424-6.
- 9 Rajiah P, Sinha R, Cuevas C, Dubinsky TJ, Bush WH Jr, Kolokythas O.Imaging of uncommon retroperitoneal masses.Radiographics 2011;31:949-76.
- 10 Pui MH,Liu MJ,Guo Y,Chen YM.Computed tomography of retroperitoneal paragangliomas.AustralasRadiol 1999;43:303-6.
- 11 Bryant RL, Stevenson DR, Hunton DW, Westbrook KC, Casali RE.Primary malignant retroperitoneal tumors.Current management.Am J Surg 1982;144:646-9.
- 12 Mikhail RA, Moore JB, Reed DN Jr, Abbott RR. Malignant retroperitoneal paragangliomas.J Surg Oncol 1986;32:32-6.